Results 121 to 130 of about 94,760 (312)

Investigating the Impact of Pretrial Detention on Sentencing Outcomes [PDF]

open access: yes, 2013
This study investigates the impact of pretrial detention on sentencing outcomes for both misdemeanors and ...
Alexander Holsinger   +2 more
core  

The ITGB2‐COPS3‐SOX2 Axis and SOX2 Liquid‐Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness

open access: yesAdvanced Science, EarlyView.
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo   +7 more
wiley   +1 more source

The Hidden Costs of Pretrial Detention [PDF]

open access: yes, 2013
This study investigates the correlation of pretrial detention with 1) pretrial outcomes (failure to appear and arrest for new criminal activity); and 2) post-disposition recidivism (new criminal activity post-disposition)
Alexander Holsinger   +2 more
core  

Inherently Disordered Auxetic Metamaterials

open access: yesAdvanced Science, EarlyView.
Inherently disordered auxetic metamaterials based on random chiral Delaunay triangulations are designed and investigated using numerical simulations and experimental tests. These disordered frameworks exhibit orthotropic behavior and a large negative Poisson's ratio (ca.
Matteo Montanari   +3 more
wiley   +1 more source

Study of Free‐Space Optical Quantum Network: Review and Prospectives

open access: yesAdvanced Science, EarlyView.
Free from the constraints of fiber connections, free‐space quantum network enables longer and more flexible quantum network connections. This review summarizes and comparatively analyzes free‐space quantum network experiments based on ground stations, satellites, and mobile platforms.
Hua‐Ying Liu, Zhenda Xie, Shining Zhu
wiley   +1 more source

Dispositions of DWI Arrestees: Anchorage, 1996 [PDF]

open access: yes, 1999
This study explores the dispositions of subjects arrested in Anchorage, Alaska during 1996 for driving while intoxicated (DWI). The project was designed to describe the Anchorage criminal justice system’s processing of DWI offenders and to isolate legal ...
Crum, Peter, Langworthy, Robert H.
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Juvenile Justice in Illinois: A Data Snapshot [PDF]

open access: yes, 2014
This new report provides an overview of juvenile justice in Illinois. This is not a research report but is intended to offer a brief primer for those who want to better understand how many young people across the state come to the attention of the ...
Mariame Kaba
core  

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

open access: yesAdvanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu   +10 more
wiley   +1 more source

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

open access: yesAdvanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv   +11 more
wiley   +1 more source

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