Results 111 to 120 of about 19,308 (244)

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

open access: yesImmunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu   +24 more
wiley   +1 more source

Combined Surgical Techniques for the Management of Malignant Glaucoma

open access: yesJournal of Ophthalmology, 2018
Purpose. To characterize new combined surgical techniques for the management of malignant glaucoma. Methods. In a retrospective, interventional case series, goniosynechialysis, peripheral iridectomy, zonulo-hyaloidectomy, and anterior vitrectomy, with or
Jinfei Tang, Ergang Du, Xingyu Li
doaj   +1 more source

At the pillar of the proverbial Golden Calf: Sacrificing the Need for ‘Responsible Knowing’ on the Altar of a Compliance-Based Ethic [PDF]

open access: yes, 2017
Evidence-based practice (EBP) has been promoted and adopted broadly and has led to advances in health and human services. Notwithstanding the underlying rationale of EBP philosophy to diversify the current body of information concerning evidence-based ...
Williams, Izaak L
core   +1 more source

A spectral analysis extension to DEMATEL for strategic leverage points identification

open access: yesInternational Transactions in Operational Research, EarlyView.
Abstract Efforts to intervene in complex systems often emphasize influential factors, yet system behavior is equally shaped by the relationships among them. Methods such as Decision‐Making Trial and Evaluation Laboratory (DEMATEL) map causal structures but remain descriptive and do not identify which relationships provide the greatest leverage for ...
Pavlos Delias, Kerasia Kalkitsa
wiley   +1 more source

Regulation and deregulation in industrial countries : some lessons for LDCs [PDF]

open access: yes
The United States'experience with antitrust and with directive regulation in the rail, trucking, airline, and telephone sectors offers useful lessons for developing countries.
Bradburd, Ralph, Ross, David R.
core  

‘It's Like a Horror Movie That You Walk Through’: Experiencing Horror Through Immersive Recreation

open access: yesThe Journal of American Culture, EarlyView.
ABSTRACT Horror stories have provided enjoyable forms of leisure for centuries. Over the past five decades, however, these experiences have evolved into increasingly immersive forms of popular culture. What once involved constructing the narrative world internally through reading has expanded into sensory engagement through visual and auditory media ...
Susan Weidmann
wiley   +1 more source

Misdirected Criticisms

open access: yesAmerican Journal of Public Health, 2012
Marc, Stifelman   +4 more
openaire   +3 more sources

Visual Arts, Insecurity and an Elusive Peace in Casamance, Senegal

open access: yesInternational Journal of Art &Design Education, EarlyView.
Abstract The separatist rebellion in Casamance, southern Senegal, has driven what is arguably the longest‐running intra‐state conflict in West Africa. Spanning over four decades, it has affected successive generations through insecurity (including armed violence and landmine use); economic disruption; trauma; human displacement (both internal and into ...
Martin Evans
wiley   +1 more source

The Origins of Computational Mechanics: A Brief Intellectual History and Several Clarifications [PDF]

open access: yes, 2017
The principle goal of computational mechanics is to define pattern and structure so that the organization of complex systems can be detected and quantified.
Crutchfield, James P.
core   +1 more source

The Epistemic Harms of Botched Apologies for Past Wrongs

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT Apologies often create expectations of meaningful change and repair. Yet when institutions or states deliver apologies for past wrongs that lack substantive reparative action, they risk deepening, rather than redressing, the harms they acknowledge.
Abraham Tobi
wiley   +1 more source

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