Results 41 to 50 of about 19,308 (244)

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution

Advanced Science, EarlyView.
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su, Huimin Pan, Yaqiang Liu, Wei Wang, Yang Jiao, Yumo Hang, Xiahe Huang, Yong E. Zhang, Yuhang Chen, Mei Ding, Xun Huang   +10 more
wiley   +1 more source

The Study of Figurative Terracottas: A Cautionary Tale from a Personal Perspective

Les Carnets de l’ACoSt, 2019
In the study of Greek figurative terracottas there are many pitfalls that have resulted from out-dated notions that continue to influence coroplastic scholarship.
Jaimee P. Uhlenbrock
doaj   +1 more source

Nostalgia videogames as playable game criticism [PDF]

, 2016
The aim of this paper is to consider the emergence of nostalgia videogames in the context of playable game criticism. Mirroring the development of the nostalgia film in cinema, an increasing number of developers are creating videogames that are evocative
Sloan, Robin J. S.
core   +2 more sources

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

High‐Security X‐Ray Imaging Encryption Based on Irreversible Acid‐Responsive Radioluminescence Memory Scintillator

Advanced Science, EarlyView.
An irreversible acid‐responsive radioluminescence memory scintillator, Zn1.3Ga1.4Ge0.3O4:Cr3+@Zn2GeO4:Eu3+ (ZGGO@ZGO), is developed in this work. The engineered dual‐layer security system composed of ZGGO@ZGO and ZGO achieves a combined effect of visual misdirection and sequential logic gates requiring acid treatment and CCD detection, significantly ...
Lin Liu, Shanshan Peng, Hanjing Guo, Linping He, Xiaofang Luo, Zixuan Li, Lisen Lin, Huanghao Yang   +7 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Microsaccades reflect the dynamics of misdirected attention in magic

Journal of Eye Movement Research, 2019
The methods of magicians provide powerful tools for enhancing the ecological validity of laboratory studies of attention. The current research borrows a technique from magic to explore the relationship between microsaccades and covert attention under ...
Anthony S. Barnhart, Francisco M. Costela, Susana Martinez-Conde, Stephen L. Macknik, Stephen D. Goldinger   +4 more
doaj   +1 more source

Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery

Annals of Gastroenterological Surgery, EarlyView.
This review critically reassesses our prior hypothesis and proposes a revised anatomical model of the fusion fascia that is broadly applicable to GI cancer surgeries grounded in the principles of mesenteric resection. Our synthesis suggests that the fusion fascia is neither a dense connective tissue membrane nor a remnant of mesothelial fusion, but ...
Hisashi Shinohara, Yasunori Kurahashi, Jun Watanabe, Yuichi Nagakawa, Tatsuro Nakamura, Eiichiro Nakao, Yudai Hojo, Shugo Kohno, Motoki Murakami, Yoshinori Ishida   +9 more
wiley   +1 more source

23/25 Gauge MIVS Trocar-Cannula as a Rescue Measure In Difficult Situations in Phacoemulsification

Delhi Journal of Ophthalmology, 2017
We describe a technique of using a small-gauge (23/25G), single, sutureless transconjunctival pars plana sclerotomy to ease phacoemulsification in eyes with a shallow anterior chamber and high intraocular pressure (phacomorphic glaucoma and following ...
Shashi Nath Jha, Nidhi Panwar, Amit Khosla, Neeraj Manchanda, Kirti Jaisingh, Anjani Khanna   +5 more
doaj   +1 more source