Results 41 to 50 of about 489,572 (304)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

A Novel Reverse Combination Configuration to Reduce Mismatch Loss for Stratospheric Airship Photovoltaic Arrays

Applied Sciences
Enhancing the output power of stratospheric airship photovoltaic arrays during months with weak irradiance is crucial for extending the endurance of airships.
Chuan Shan, Kangwen Sun, Dongji Cheng, Xinzhe Ji, Jian Gao, Tong Zou   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A Review of Spatial Mismatch Research: Empirical Debate, Theoretical Evolution and Connotation Expansion

Land, 2022
At present, widespread urban expansion, regeneration, and transformation have inevitably led to the spatial separation of residence and employment, and negatively affected the employment welfare of the subjects concerned, which needs to be traced back to
Liping Wang, Cifang Wu, Songnian Zhao
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Mitigation of mismatch losses in solar PV systems: a hybrid L-shaped propagated array configuration approach

Frontiers in Energy Research
There has been a global expansion of solar electricity during the past decades. Solar photovoltaic (PV) electricity generation is not only simple but also environmentally benign and cost-effective.
Belqasem Aljafari, S. Devakirubakaran, Praveen Kumar Balachandran, Sudhakar Babu Thanikanti   +3 more
doaj   +1 more source

Event-Driven Control for Switched Systems With Quantization and Packet Loss

IEEE Access, 2020
In this paper, the problem of designing the quantized feedback controller for a class of continuous-time switched systems with packet loss and event-driven scheme is considered.
Jingjing Yan, Xinjing Wang, Li MA, Chi Zhang   +3 more
doaj   +1 more source

LambdaFM: Learning Optimal Ranking with Factorization Machines Using Lambda Surrogates [PDF]

, 2016
State-of-the-art item recommendation algorithms, which apply Factorization Machines (FM) as a scoring function and pairwise ranking loss as a trainer (PRFM for short), have been recently investigated for the implicit feedback based context-aware ...
Chen, Long, Guo, Guibing, Jose, Joemon M., Yu, Haitao, Yuan, Faije, Zhang, Weinan   +5 more
core   +1 more source

Global and Regional Temporal Changes in Cross‐Country Inequalities of Site‐Specific Osteoarthritis Burden, 1990 to 2021

Arthritis Care &Research, EarlyView.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rates (ASYRs) for site‐specific OA across 204 countries and territories were obtained from the Global Burden of Diseases, Injuries, and ...
Haowei Chen, Lei Si, David J. Hunter, Lei Zhang, Zhe‐Sheng Chen, Xiaomeng Wang, Vicky Duong, Zhounan Zhou, Peihua Cao, Han Cen, Su'an Tang, Tianyu Chen, Houjun Xue, Zhaohua Zhu, Changhai Ding   +14 more
wiley   +1 more source

Gain-through-filtering enables tuneable frequency comb generation in passive optical resonators

Nature Communications, 2019
In normal dispersion, modulation instability, which is a precursor of Kerr combs, is forbidden due to phase mismatch. Here, the authors show the compensation of such phase mismatch by introducing frequency-dependent loss using a notch filter, hence ...
Florent Bessin, Auro M. Perego, Kestutis Staliunas, Sergei K. Turitsyn, Alexandre Kudlinski, Matteo Conforti, Arnaud Mussot   +6 more
doaj   +1 more source