Results 91 to 100 of about 1,156,590 (255)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Primary care medication safety surveillance with integrated primary and secondary care electronic health records: a cross-sectional study [PDF]

, 2015
Introduction: The extent of preventable medication-related hospital admissions and medication-related issues in primary care is significant enough to justify developing decision support systems for medication safety surveillance.
AG Winterstein, AJ Avery, AJ Avery, Anthony Avery, Artur Akbarov, B Guthrie, CJ Morris, Darren M. Ashcroft, E Kontopantelis, Evangelos Kontopantelis, H Akaike, H Wickham, HM Holmes, I Schubert, Iain Buchan, J Penge, KC Nanji, Matthew Sperrin, MH Beers, MN O’Connor, NS Wenger, P Gallagher, P Gallagher, R Galvin, R Spencer, Richard Williams, RL Howard, S Nakagawa, Sarah Rodgers, Susan J. Stocks   +29 more
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Exploring experiences and perceptions of nursing students regarding missed nursing care in Ethiopia: a descriptive qualitative study

BMC Nursing
Background Missed nursing care is a critical issue, particularly in resource-limited settings. Nursing students may encounter missed nursing care during clinical placements.
Muktar Abawaji, Rachel Cardwell, Gugsa Germossa, Lisa McKenna   +3 more
doaj   +1 more source

Probabilistic linkage to enhance deterministic algorithms and reduce data linkage errors in hospital administrative data. [PDF]

, 2017
BACKGROUND: The pseudonymisation algorithm used to link together episodes of care belonging to the same patients in England (HESID) has never undergone any formal evaluation, to determine the extent of data linkage error.
Aldridge, Robert, Gilbert, Ruth, Goldstein, Harvey, Hagger-Johnson, Gareth, Harron, Katie   +4 more
core   +3 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Improving WIC Retention in Vermont: Beneficiary attitudes toward co-location in medical homes [PDF]

, 2015
Introduction: The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is a national program aimed at improving the nutrition and health of pregnant women and children.
Bister, Donna, Chang, Lillian, Fu, Eunice, Howe, Allison K., Pichiotino, Erin, Taylor, Sasha, Till, Brian, Triano, Amy, Whitson, Jenna, Whittier, John   +9 more
core   +1 more source

Quantum-mechanical description of in-medium fragmentation

, 2008
We present a quantum-mechanical description of quark-hadron fragmentation in a nuclear environment. It employs the path-integral formulation of quantum mechanics, which takes care of all phases and interferences, and which contains all relevant time ...
A. V. Tarasov, B. Z. Kopeliovich, B. Z. Kopeliovich, B. Z. Kopeliovich, B. Z. Kopeliovich, B. Z. Kopeliovich, B. Z. Kopeliovich, B. Z. Kopeliovich, H.-J. Pirner, I. K. Potashnikova, Ivan Schmidt, O. O. Voskresenskaya, R. P. Feynman, Y. Van Haarlem   +13 more
core   +1 more source

Data Analytics and Modeling for Appointment No-show in Community Health Centers [PDF]

, 2018
Objectives: Using predictive modeling techniques, we developed and compared appointment no-show prediction models to better understand appointment adherence in underserved populations.
Doebbeling, Bradley N., Mohammadi, Iman, Toscos, Tammy, Turkcan, Ayten, Wu, Huanmei   +4 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source