Results 311 to 320 of about 1,544,422 (378)

Synthetic biology approaches to generate temperature‐sensitive alleles for the Sterile Insect Technique

Insect Science, EarlyView.
Abstract The Sterile Insect Technique (SIT) is an environmentally friendly, sustainable pest control approach, which uses large‐scale releases of sterile insects to suppress or eradicate target populations through infertile matings. The efficiency of SIT is enhanced by male‐only releases requiring genetic sexing strains (GSSs) that are classically ...
Chun Yin Leung, Ernst A. Wimmer, Hassan M. M. Ahmed   +2 more
wiley   +1 more source

The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations [PDF]

Heather A. Baker, Jonathan P. Bernardini, Veronika Csizmók, Angel M. Madero, Shriya Kamat, H.L Eng, Jessica Lacoste, Faith Au Yeung, Sophie A. Comyn, Gaetano Calabrese, Brian Raught, Mikko Taipale, Thibault Mayor   +12 more
openalex   +1 more source

Hox Gene Variation Drives Morphological Specialization of Humpback Grouper Cromileptes altivelis

Integrative Zoology, EarlyView.
Cromileptes altivelis exhibits a distinctive “sunken head and humpback” morphology, formed through cranial remodeling. Genetic analyses identified unique amino acid variants in Hoxa7a and Hoxa10b, with functional tests confirming their role in enhancing osteoblast activity and driving cranial remodeling.
Xiaoying Cao, Zhaowei Zhong, Lisheng Wu, Quanyin Liu, Shaoxiong Ding   +4 more
wiley   +1 more source

Identification of a Missense Mutation in the FLNC Gene from a Chinese Family with Restrictive Cardiomyopathy [Letter]. [PDF]

J Multidiscip Healthc
Idrus HH.
europepmc   +1 more source

Museomics Deciphers the Phylogeographic Differentiation and Conservation Status of a Montane Pheasant

Integrative Zoology, EarlyView.
Museum specimens provide a rich source of historical DNA, enabling insights into phylogenetic relationships and demographic history of the endangered Koklass Pheasant. Our findings uncovered a previously unrecognized population in Guizhou province and highlighted elevated extinction risk in populations from Anhui province and Southern China, informing ...
Zhiyong Jiang, Yalin Cheng, Shuai Zhang, Wenqing Zang, Peng He, Dezhi Zhang, Jinjuan Mei, Peng Cui, Yanhua Qu, Hailong Wu   +9 more
wiley   +1 more source

Compound heterozygosity of a De novo 16q24.1 deletion and missense mutation in COX4I1 leads to developmental regression, intellectual disability, and seizures. [PDF]

Epilepsia Open
Liu Z, He M, Luo X, Pan H, Mao X, Su J.
europepmc   +1 more source

Does Sickle Cell Anaemia Have a Relationship With Avascular Pulp Necrosis? A Systematic Review

Australian Endodontic Journal, EarlyView.
ABSTRACT This systematic review examined the relationship between sickle cell disease (SCD), an inherited genetic hemoglobinopathy, and avascular pulp necrosis (APN) in intact teeth. A comprehensive search of eight electronic databases was performed up to December 2024.
Elidiane Elias Ribeiro, Karin Sá Fernandes, Erika Sales Joviano Pereira, Angelica Maria Cupertino Lopes Marinho, Jefferson R. Tenório, Márcia Pereira Alves dos Santos   +5 more
wiley   +1 more source

Dissecting KMT2D missense mutations in Kabuki syndrome patients

, 2018
Dario Cocciadiferro, Bartolomeo Augello, Pasquelena De Nittis, Jiyuan Zhang, Barbara Mandriani, Natascia Malerba, Gabriella Maria Squeo, Alessandro Romano, Barbara Piccinni, Tiziano Verri, Lucia Micale, Laura Pasqualucci, Giuseppe Merla   +12 more
openalex   +2 more sources

Pre-gestational diabetes in a young woman with a pathogenic INSR missense mutation, p.(Met1180Lys). [PDF]

Endocrinol Diabetes Metab Case Rep
Prehn EL, Crowley M, Fennell D, Kinsley BT, Colclough K, Byrne MM.   +5 more
europepmc   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source