Results 41 to 50 of about 1,716,816 (278)

bcROCsurface: an R package for correcting verification bias in estimation of the ROC surface and its volume for continuous diagnostic tests

open access: yesBMC Bioinformatics, 2017
Background Receiver operating characteristic (ROC) surface analysis is usually employed to assess the accuracy of a medical diagnostic test when there are three ordered disease status (e.g. non-diseased, intermediate, diseased). In practice, verification
Khanh To Duc
doaj   +1 more source

Extended Kalman filtering with stochastic nonlinearities and multiple missing measurements [PDF]

open access: yes, 2012
Copyright @ 2012 ElsevierIn this paper, the extended Kalman filtering problem is investigated for a class of nonlinear systems with multiple missing measurements over a finite horizon.
Basin   +38 more
core   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

Multiple imputation with missing indicators as proxies for unmeasured variables: simulation study

open access: yesBMC Medical Research Methodology, 2020
Background Within routinely collected health data, missing data for an individual might provide useful information in itself. This occurs, for example, in the case of electronic health records, where the presence or absence of data is informative.
Matthew Sperrin, Glen P. Martin
doaj   +1 more source

A flexible approach for variable selection in large-scale healthcare database studies with missing covariate and outcome data

open access: yesBMC Medical Research Methodology, 2022
Background Prior work has shown that combining bootstrap imputation with tree-based machine learning variable selection methods can provide good performances achievable on fully observed data when covariate and outcome data are missing at random (MAR ...
Jung-Yi Joyce Lin   +5 more
doaj   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Implementing Multiple Imputation for Missing Data in Longitudinal Studies When Models are Not Feasible: An Example Using the Random Hot Deck Approach

open access: yesClinical Epidemiology, 2022
Chinchin Wang,1,2 Tyrel Stokes,3 Russell J Steele,3 Niels Wedderkopp,4 Ian Shrier1 1Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, H3T 1E2, Canada; 2Department of Epidemiology ...
Wang C   +4 more
doaj  

Regularized Mislevy-Wu Model for Handling Nonignorable Missing Item Responses

open access: yesInformation, 2023
Missing item responses are frequently found in educational large-scale assessment studies. In this article, the Mislevy-Wu item response model is applied for handling nonignorable missing item responses.
Alexander Robitzsch
doaj   +1 more source

Bearing-only acoustic tracking of moving speakers for robot audition [PDF]

open access: yes, 2015
This paper focuses on speaker tracking in robot audition for human-robot interaction. Using only acoustic signals, speaker tracking in enclosed spaces is subject to missing detections and spurious clutter measurements due to speech inactivity ...
Evers, C   +4 more
core   +2 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

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