Results 71 to 80 of about 1,716,816 (278)

Economic Aspects of the Missing Data Problem – the Case of the Patient Registry

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2017
Registries are indispensable in medical studies and provide the basis for reliable study results for research questions. Depending on the purpose of use, a high quality of data is a prerequisite.
Hatice Uenal, David Hampel
doaj   +1 more source

A probabilistic approach to value sets of polynomials over finite fields [PDF]

open access: yes, 2014
In this paper we study the distribution of the size of the value set for a random polynomial with degree at most $q-1$ over a finite field $\mathbb{F}_q$.
Gao, Zhicheng, Wang, Qiang
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

A new estimator for population total in the presence of missing data under unequal probability sampling without replacement: A case study on fine particulate matter in Northern Thailand [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2023
The issue of fine particulate matter in Thailand, especially in Northern Thailand, is an urgent problem that needs to be solved because of potential harm to human health. Prior estimates of fine particulate matter help planning how to reduce it.
Chugiat Ponkaew, Nuanpan Lawson
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

A nonparametric multiple imputation approach for missing categorical data

open access: yesBMC Medical Research Methodology, 2017
Background Incomplete categorical variables with more than two categories are common in public health data. However, most of the existing missing-data methods do not use the information from nonresponse (missingness) probabilities.
Muhan Zhou   +3 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Exploring the impact of missing data on maternal tobacco program results: an analysis of self-efficacy on smoking cessation

open access: yesBMC Public Health
Background Tobacco use is a major contributor to chronic illnesses worldwide, leading to significant morbidity and mortality. Effective tobacco cessation programs are crucial in reducing the health risks associated with smoking.
Mengting Zhao, Benjamin Langworthy
doaj   +1 more source

Second-Order Inference for the Mean of a Variable Missing at Random [PDF]

open access: yes, 2015
We present a second-order estimator of the mean of a variable subject to missingness, under the missing at random assumption. The estimator improves upon existing methods by using an approximate second-order expansion of the parameter functional, in ...
Carone, Marco   +2 more
core   +2 more sources

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