Results 61 to 70 of about 4,225,561 (321)

Informative missingness in electronic health record systems: the curse of knowing

open access: yesDiagnostic and Prognostic Research, 2020
Electronic health records provide a potentially valuable data source of information for developing clinical prediction models. However, missing data are common in routinely collected health data and often missingness is informative.
Rolf H. H. Groenwold
doaj   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura   +5 more
wiley   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser   +6 more
wiley   +1 more source

Calibrated imputation of numerical data under linear edit restrictions [PDF]

open access: yes, 2008
A common problem faced by statistical offices is that data may be missing from collected data sets. The typical way to overcome this problem is to impute the missing data.
De Waal, Ton   +2 more
core  

MissForest - nonparametric missing value imputation for mixed-type data

open access: yes, 2011
Modern data acquisition based on high-throughput technology is often facing the problem of missing data. Algorithms commonly used in the analysis of such large-scale data often depend on a complete set.
D. J. Stekhoven   +11 more
core   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd   +3 more
wiley   +1 more source

A simplified eye-opener on managing missing data and in evaluation of non-response bias in medical research: a narrative review

open access: yesJournal of the College of Community Physicians, 2018
Using correct methods for prevention, analysis and treatment of missing data is essential in preserving the validity of scientific research. In spite of this, issues related to missing data and non-response bias are found to be inadequately discussed in ...
P. K. B. Mahesh   +4 more
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez   +13 more
wiley   +1 more source

Missing Data Analysis

open access: yesAnnual Review of Clinical Psychology
Methods for handling missing data in clinical psychology studies are reviewed. Missing data are defined, and a taxonomy of main approaches to analysis is presented, including complete-case and available-case analysis, weighting, maximum likelihood, Bayes, single and multiple imputation, and augmented inverse probability weighting.
openaire   +2 more sources

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