Results 61 to 70 of about 4,202,897 (320)

Oncogenic NRAS Mutation in Incipient Sarcomatous Transformation of Cystic Nephroma From a Patient With DICER1‐Related Tumor Predisposition Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Anaplastic sarcoma of the kidney (ASK) is a DICER1‐associated malignant tumor presumed to arise in a benign precursor, pediatric cystic nephroma (PCN). However, the initial oncogenic alteration(s) associated with malignant transformation are unknown.
Nahir Cortes‐Santiago, Sarah B. Whittle, Sarah Scollon, Sharon E. Plon, Sanjeev Vasudevan, Bryony J. Lucas, Angshumoy Roy   +6 more
wiley   +1 more source

Simultaneous SNP identification in association studies with missing data

, 2012
Association testing aims to discover the underlying relationship between genotypes (usually Single Nucleotide Polymorphisms, or SNPs) and phenotypes (attributes, or traits).
Casella, George, Davis, John M., Gopal, Vikneswaran, Li, Xiaobo, Li, Zhen   +4 more
core   +1 more source

Preoperative Cytopenia in Patients Affected by High‐Risk Neuroblastoma: Just a Matter of Platelets?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims In patients affected by high‐risk neuroblastoma (HR‐NB), complete macroscopic resection (CMR) is associated with better outcomes. These patients are often cytopenic due to intensive induction regimens. The aim of the present study is to assess the impact of preoperative cytopenia on surgical outcome in patients with HR‐NB ...
Giorgio Persano, Valerio Voglino, Federico Beati, Cristina Martucci, Chiara Grimaldi, Francesca Del Bufalo, Annalisa Serra, Francesco Fabozzi, Carmen Malaspina, Pier Luigi Di Paolo, Gian Luigi Natali, Simone Reali, Maria Antonietta De Ioris, Alessandro Crocoli   +13 more
wiley   +1 more source

Missing Data, Speculative Reading

Journal of Cultural Analytics
In this article we use an approach we term “speculative reading” to explore gaps in Sylvia Beach’s lending library records and the *Shakespeare and Company Project* datasets.
Rebecca Sutton Koeser, Zoe LeBlanc
doaj   +1 more source

Informative missingness in electronic health record systems: the curse of knowing

Diagnostic and Prognostic Research, 2020
Electronic health records provide a potentially valuable data source of information for developing clinical prediction models. However, missing data are common in routinely collected health data and often missingness is informative.
Rolf H. H. Groenwold
doaj   +1 more source

Relation of Adverse Childhood Experiences to Clinical and Patient‐Reported Outcomes for Adults With Sickle Cell Disease: A Registry Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell, Jessica Liang, Liliana Preiss, Angela Rivers, Jane S. Hankins, Allison King, Justin Williams, Michael B. Potter, Danielle Hessler   +8 more
wiley   +1 more source

Scalable Tensor Factorizations for Incomplete Data

, 2010
The problem of incomplete data - i.e., data with missing or unknown values - in multi-way arrays is ubiquitous in biomedical signal processing, network traffic analysis, bibliometrics, social network analysis, chemometrics, computer vision, communication
Acar, Acar, Acar, Acar, Andersson, Bader, Bro, Buchanan, Carroll, Daniel M. Dunlavy, Delorme, Dempster, Dunlavy, Evrim Acar, Gabriel, Geng, Harshman, Kiers, Kolda, Kolda, Kruskal, Miwakeichi, Morten Mørup, Moré, Mørup, Nocedal, Orekhov, Paatero, Ruhe, Srebro, Tamara G. Kolda, Tomasi, Tucker, Uhlig, Walczak, Zhang   +35 more
core   +1 more source

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt, Antje Walz, Dietrich Knoerzer   +2 more
wiley   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

A simplified eye-opener on managing missing data and in evaluation of non-response bias in medical research: a narrative review

Journal of the College of Community Physicians, 2018
Using correct methods for prevention, analysis and treatment of missing data is essential in preserving the validity of scientific research. In spite of this, issues related to missing data and non-response bias are found to be inadequately discussed in ...
P. K. B. Mahesh, Wasantha Gunathunga, Mahendra arnold, S. B. Munasinghe, Sinha De Silva   +4 more
doaj   +1 more source