Results 121 to 130 of about 287,343 (334)

Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham   +14 more
wiley   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan   +9 more
wiley   +1 more source

Comparison of different approaches in handling missing data in longitudinal multiple-item patient-reported outcomes: a simulation study

open access: yesHealth and Quality of Life Outcomes
Background Patient-reported outcomes (PROs) are important clinical outcomes widely used as primary and secondary endpoints in clinical studies. However, PRO data often suffers from missing values for various reasons, which pose challenges to data ...
Minqian Yan   +4 more
doaj   +1 more source

Weak consistency of the 1-nearest neighbor measure with applications to missing data

open access: yes, 2019
When data is partially missing at random, imputation and importance weighting are often used to estimate moments of the unobserved population. In this paper, we study 1-nearest neighbor (1NN) importance weighting, which estimates moments by replacing ...
Sharpnack, James
core  

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

open access: yesAdvanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer   +10 more
wiley   +1 more source

Imputation and Price Indexes: Theory and Evidence from the International Price Program [PDF]

open access: yes
The goal of this paper is to theoretically and empirically demonstrate the consequences of different imputation methods, using recent data from the International Price Program. We suppose that prices are missing due to random or erratic reporting.
Erwin Diewert, Robert Feenstra
core  

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