Results 31 to 40 of about 161,037 (263)

Impact of Missing Data on Data Quality in Social Research

open access: yesСоціологічні студії
Missing data is a common issue in quantitative social research that negatively affects the data quality. This article explores the consequences of missing data, outlining the potential issues it may pose and emphasizing the importance of properly ...
Yaroslav Kostenko
doaj   +1 more source

Methods to Handle Incomplete Data

open access: yesMAMC Journal of Medical Sciences, 2020
Context: The major question for data analysis is determining the appropriate analytic approach in the presence of incomplete observations. The most common solution to handle missing data in a data set is imputation, where missing values are estimated and
Vinny Johny   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Missing-Data Handling Methods for Lifelogs-Based Wellness Index Estimation: Comparative Analysis With Panel Data

open access: yesJMIR Medical Informatics, 2020
BackgroundA lifelogs-based wellness index (LWI) is a function for calculating wellness scores based on health behavior lifelogs (eg, daily walking steps and sleep times collected via a smartwatch).
Kim, Ki-Hun, Kim, Kwang-Jae
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Handling missing data in research

open access: yesPerspectives in Clinical Research
Missing data are an inevitable part of research and lead to a decrease in the size of the analyzable population, and biased and imprecise estimates. In this article, we discuss the types of missing data, methods to handle missing data and suggest ways in
Priya Ranganathan, Sally Hunsberger
doaj   +1 more source

Machine-Learning-Based Imputation Method for Filling Missing Values in Ground Meteorological Observation Data

open access: yesAlgorithms, 2023
Ground meteorological observation data (GMOD) are the core of research on earth-related disciplines and an important reference for societal production and life.
Cong Li, Xupeng Ren, Guohui Zhao
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Missing Data Imputation for Classification Problems

open access: yesCoRR, 2020
27 pages, 5 ...
Arkopal Choudhury, Michael R. Kosorok
openaire   +2 more sources

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