Results 231 to 240 of about 2,401,098 (314)

Modeling qualitative between-person heterogeneity in time series using latent class vector autoregressive models. [PDF]

Behav Res Methods
Ernst AF, Haslbeck JMB.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Occurrence of advance care planning for persons with dementia, cancer and other chronic-progressive diseases in general practice: longitudinal analysis of data from health records linked with administrative data. [PDF]

BMJ Open
Hommel D, Azizi B, Visser M, Bolt SR, Blom JW, Janssen DJA, van Hout HPJ, Francke AL, Verheij RA, Joling KJ, van der Steen JT.   +10 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Barriers to providing long-term care for persons with spinal cord injury in Switzerland: a qualitative study of service delivery and workforce challenges. [PDF]

BMC Health Serv Res
Lussi C, Schwegler R, Friedli M, Stock M, Bickenbach J, Zanini C, Eriks-Hoogland I, Hund-Georgiadis M, Zipser CM, Jordan X, Sabariego C.   +10 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Demographic and Clinical Characteristics of Patients With Hepatitis C and Hepatitis B Co-Infection, Georgia, 2017-2023. [PDF]

J Viral Hepat
Handanagic S, Shadaker S, BaliashvilI D, Schumacher IT, Armstrong PA, Tohme RA, Butsashvili M.   +6 more
europepmc   +1 more source

Generation of offspring by reproduction simulated virtual applied to the problem of missing persons

, 2011
Martha Isabel Cárdenas Esguerra
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Disability inclusion in the Brazilian health system: results of a health system assessment. [PDF]

Glob Health Action
Polack S, Delgado Ramos V, Sepúlveda Köptcke L, de Araujo Morais I, Reichenberger V, Scherer N, Veloso de Albuquerque MDS, Kuper H, Lyra TM, Moran de Brito CM.   +9 more
europepmc   +1 more source