Results 231 to 240 of about 998,037 (295)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Communication from the Commission on violence against children, young persons and women. Proposal for a Council Decision on a medium-term Community action programme on measures providing a Community-wide support to Member States action relating to violence against children, young persons and women (Daphne Programme) (2000-2004). COM (98) 335 final, 20 May 1998 [PDF]

, 1998

core  

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Multiple imputation of multilevel data with single-level models: A fully conditional specification approach using adjusted group means. [PDF]

Behav Res Methods
Grund S, Lüdtke O, Robitzsch A.
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

The All-Payer Claims Database After the Gobeille Supreme Court Decision: Assessing the Impact on Fatal Opioid-Related Overdose Research. [PDF]

Health Serv Res
Cordes J, Bauer C, Bernson D, Larochelle MR, Li W, Cao J, Dammann O, Stopka TJ.   +7 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Suicidal thoughts, problem gambling severity and utilisation of health care and social services: A population-based study in Finland. [PDF]

Addict Behav Rep
Latvala T, Heiskanen M, Marionneau V, Lind K, Grönroos T, Castrén S.   +5 more
europepmc   +1 more source

Structured telemonitoring reduces HbA1c and emergency visits in insulin-treated type 2 diabetes: a controlled cohort study in Ecuador's public hospital. [PDF]

Front Clin Diabetes Healthc
Santillán A, Travez Proaño EI, Jaramillo Encalada IN, Abril López PA, Tricallotis J, Acosta-España JD.   +5 more
europepmc   +1 more source

The Participation of Older Persons in the Adoption of Age-Friendly Care Models in Hospital Settings: A Scoping Review. [PDF]

Nurs Health Sci
Millar NA, Hunter KF, Dahlke S, Tate K, Alagadan IJ, Hoben M.   +5 more
europepmc   +1 more source