Multiple Imputation Approaches Applied to the Missing Value Problem in Bottom-Up Proteomics. [PDF]
Int J Mol Sci, 2021 Gardner ML, Freitas MA.
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Exploiting Missing Value Patterns for a Backdoor Attack on Machine Learning Models of Electronic Health Records: Development and Validation Study. [PDF]
JMIR Med Inform, 2022 Joe B, Park Y, Hamm J, Shin I, Lee J.
europepmc +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Missing Value Imputation With Low-Rank Matrix Completion in Single-Cell RNA-Seq Data by Considering Cell Heterogeneity. [PDF]
Front Genet, 2022 Huang M, Ye X, Li H, Sakurai T.
europepmc +1 more source
Methods to handle missing values and missing individuals [PDF]
European Journal of Epidemiology, 2018 Carl Bonander, Ulf Strömberg
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Missing Value Imputation of Time-Series Air-Quality Data via Deep Neural Networks. [PDF]
Int J Environ Res Public Health, 2021 Kim T, Kim J, Yang W, Lee H, Choo J.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Multiple Imputation via Generative Adversarial Network for High-dimensional Blockwise Missing Value Problems. [PDF]
Proc Int Conf Mach Learn Appl, 2021 Dai Z, Bu Z, Long Q.
europepmc +1 more source