Results 101 to 110 of about 1,170,104 (261)

ENHANCING 〖PM〗_(2.5) PREDICTION IN KEMAYORAN DISTRICT, DKI JAKARTA USING DEEP BILSTM METHOD

open access: yesBarekeng
Worldwide air pollution is a concern, and this is especially true in Indonesia, where most people breathe air that is more contaminated than recommended by the WHO. The concentration of  presents notable health hazards.
Nabila Karin   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Stackade Ensemble Learning for Resilient Forecasting Against Missing Values, Adversarial Attacks, and Concept Drift

open access: yesApplied Sciences
Machine learning is often implemented in smart grids to help with electricity load forecasts, which are challenging to process or compute using conventional approaches.
Mohd Hafizuddin Bin Kamilin   +1 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Missing value replacement in strings and applications

open access: yesData Mining and Knowledge Discovery
Abstract Missing values arise routinely in real-world sequential (string) datasets due to: (1) imprecise data measurements; (2) flexible sequence modeling, such as binding profiles of molecular sequences; or (3) the existence of confidential information in a dataset which has been deleted deliberately for privacy protection.
G. Bernardini (Giulia)   +6 more
openaire   +7 more sources

Estimation of instantaneous peak flows in Canadian rivers: an evaluation of conventional, nonlinear regression, and machine learning methods

open access: yesWater Science and Technology
Instantaneous peak flows (IPFs) are often required to derive design values for sizing various hydraulic structures, such as culverts, bridges, and small dams/levees, in addition to informing several water resources management-related activities. Compared
Muhammad Naveed Khaliq
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Handling of Missing Values in Lexical Acquisition

open access: yesProceedings of the Language Resources and Evaluation Conference, 2010
Comunicació presentada a: 7th Conference on International Language Resources and Evaluation, celebrada a Valletta, Malta, del 17 al 23 de maig de 2010.
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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