Results 31 to 40 of about 194,933 (329)

My Pilgrimage to the Missional in South Africa

open access: yesEcclesial Futures, 2021
The Dutch Reformed Church in South Africa at its 2013 General Synod made a bold resolution—to be a missional church. This resolution was not only an acknowledgement of past failures, but also a commitment to deep and lasting reform.
Coenie Burger
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

�n Stormkompas in tye van aanpasbare verandering � kontoere van mission�re leierskap

open access: yesVerbum et Ecclesia, 2008
A compass in the storms of adaptive change - outlines on missional leadership.The article describes outlines of and elaborates on missional leadership in the challenging times of adaptive change.
C J P Niemandt
doaj   +1 more source

A partnership for prosperity agency: A case study of InnerCHANGE South Africa

open access: yesTheologia Viatorum, 2020
Practical ways to serve African communities of poverty motivated this case study. It explores how the church could be missional as an agent of prosperity in communities of poverty.
Kasebwe T.L. Kabongo
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

A missional hermeneutic for the transformation of theological education in Africa

open access: yesHTS Teologiese Studies/Theological Studies, 2019
The wide acceptance and maturation of the theology of missio Dei is the most important development in the theology of mission in recent times. It introduced a radically new understanding of mission and theology, and flowing from that a re-appropriation ...
Nelus Niemandt
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Called and sent to make a difference: Radical missionality

open access: yesVerbum et Ecclesia, 2017
The concept missional is well established within the so-called missional conversation. It is however often questioned by scholars and pastors for different reasons.
Malan Nel
doaj   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

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