Results 21 to 30 of about 66,093 (250)
African Journal on Land Policy and Geospatial Sciences, 2022 Sr. Dr. Elizabeth W. Wanyoike, ESM Lizwangu20@gmail.com, Farragut, US ABSTRACT Context and background In the last few years, in some African countries such as Burundi, Rwanda, and Kenya the churches were burnt down; refugees in these ...
Elizabeth Wangui Wanyoike
doaj
Conquests of Memory: Franciscan Chronicles of the East Asian Church in the Early Modern Period
Culture & History Digital Journal, 2016 This essay examines the ways in which Franciscan authors recounted the history of their missions in East Asia from the sixteenth to the eighteenth century. Key differences between Franciscan authors and those of other orders are highlighted, with special
Liam Matthew Brockey
doaj +1 more source
A Request Made To Sultan Abdulhamit Ii About Adana Province And Thoughts It Provoked
Gaziantep Üniversitesi Sosyal Bilimler Dergisi, 2022 The official and private requests and denouncements sent to Sultan Abdulhamid II, who wanted to be instantaneously informed about all the incidents happening inland and outland, are remarkably important sources in the context of historical studies.
Özlem Muraz Budak
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Russian Journal of Education and PsychologyBackground. The relevance of this study is determined by the urgent need to modernize patriotic education in the context of significant changes in Russian society, increased state requirements for the integration of civic, moral, and spiritual values ...
Ivan F. Paramonov
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source