Results 51 to 60 of about 51,974 (281)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Mistake of fact in polish criminal law [PDF]
, 2015 Wydział Prawa i AdministracjiAnaliza błędu uregulowanego w art. 29 k.k. prowadzi do wielu konkluzji. W pierwszym rozdziale przedstawiono rozwój instytucji błędu co do kontratypu, jego aspekt polityczno-kryminalny oraz regulację tego błędu w innych ...
Piaczyńska, Anna
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Submission to Queensland Law Reform Commission on review of consent laws and the excuse of mistake of fact [PDF]
, 2020 The purpose of this submission is to set out a comprehensive model provision for the crime of rape (or the equivalent offence) that can be incorporated into all Australian criminal jurisdictions irrespective of whether the particular legislation can be ...
Hemming, Andrew
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Mens rea - Mistake of law & mistake of fact in German criminal law: A survey for international criminal tribunals [PDF]
, 2005 More than a decade has passed since the establishment of the two ad hoc Tribunals, however, the jurisprudence of both Tribunals evidence the inconsistency regarding the requisite mens rea standards for serious violations of international humanitarian law.
Badar, ME, Badar, Mohamed
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Paving the Way for Recognizing Postpenetration Rape Through the Mistake of Fact Defense [PDF]
, 2020 On February 13, 2019, the Massachusetts Supreme Judicial Court in Commonwealth v. Sherman introduced a communication element in rape cases involving withdrawn consent.
King, Katherine M.
core +1 more source
Towards recovery for payments made under a mistake of law: Air Canada v. British Columbia [PDF]
, 1989 Introduction: At its simplest, the \"mistake of law doctrine\" holds that money paid under a mistake of law (as opposed to one of fact) is irrevocable.
McInnes, Mitchell
core +2 more sources
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Ignorance and Mistake of Criminal Law, Noncriminal Law, and Fact [PDF]
, 2012 After clarifying the distinction between mistakes of fact and mistakes of law, this article explores in detail an important distinction within the category of mistake of law, between mistake about the criminal law itself and mistake about noncriminal law
Simons, Kenneth W., Simons, Kenneth
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