Results 181 to 190 of about 10,033,806 (381)

74th ENMC International Workshop: Mitochondrial Diseases 19–20 November 1999, Naarden, The Netherlands [PDF]

, 2000
Joanna Poulton, Douglass M. Turnbull
openalex   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi009-A) from a patient with amyotrophic lateral sclerosis due to SOD1 mutation

Stem Cell Research
Amyotrophic lateral sclerosis (ALS) is a fatal neurological disorder characterized by progressive degeneration of nerve cells in the spinal cord and brain.
Bo Li, Haoran Mu, Didi Shan, Yitong Yang, Yingxin Wang, Jianing Li, Hongxu Wang, Xiaohan Sun, Xinbo Ji, Zexin Zhan, Yichang Jiao, Yao Tang, Bo Kong, Bo Gao, Yu Wang, Ping Sun, Fuchen Liu   +16 more
doaj  

Clinical Approaches for Mitochondrial Diseases. [PDF]

Cells, 2023
Hong S, Kim S, Kim K, Lee H.
europepmc   +1 more source

Multiple skeletal muscle mitochondrial DNA deletions in patients with unilateral peripheral arterial disease [PDF]

, 2000
Eric P. Brass, Hong Wang, William R. Hiatt   +2 more
openalex   +1 more source

PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. [PDF]

, 2019
Chronic gut inflammatory diseases are associated with disruption of intestinal epithelial barriers and impaired mucosal immunity. HIV-1 (HIV) causes depletion of mucosal CD4+ T cells early in infection and disruption of gut epithelium, resulting in ...
Arredondo, Juan, Cortopassi, Gino, Crakes, Katti R, Dandekar, Satya, Datta, Sandipan, Fenton, Anne, Gaulke, Christopher A, Giulivi, Cecilia, Grishina, Irina, Hirao, Lauren A, Marco, Maria L, Napoli, Eleonora, Sankaran-Walters, Sumathi, Santos Rocha, Clarissa   +13 more
core  

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

MYC-an emerging player in mitochondrial diseases. [PDF]

Front Cell Dev Biol, 2023
Purhonen J, Klefström J, Kallijärvi J.
europepmc   +1 more source

Genetic defects causing mitochondrial respiratory chain disorders and disease [PDF]

, 2000
John Christodoulou
openalex   +1 more source

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source