Results 221 to 230 of about 10,435,022 (365)

Red Flags in Primary Mitochondrial Diseases: What Should We Recognize? [PDF]

Int J Mol Sci, 2023
Conti F, Di Martino S, Drago F, Bucolo C, Micale V, Montano V, Siciliano G, Mancuso M, Lopriore P.   +8 more
europepmc   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

ATAD3 duplications bridge mitochondrial diseases and Aicardi-Goutières syndrome. [PDF]

Dev Med Child Neurol
Planté-Bordeneuve P, Bérat CM, Hanein S, Gitiaux C, ATAD3 Study Group, Steffann J, Desguerre I, Rötig A, Boddaert N, Barcia G.   +9 more
europepmc   +1 more source

Hearing Impairment and Neuroimaging Results in Mitochondrial Diseases. [PDF]

J Pers Med, 2023
Cadoni G, Primiano G, Picciotti PM, Calandrelli R, Galli J, Servidei S, Conti G.   +6 more
europepmc   +1 more source

Rescue of protein dyshomeostasis in hippocampal astrocytes from an Alzheimer’s disease mouse model by stabilizing ER-mitochondrial interactions at a 20 nm distance [PDF]

Giulia Dematteis, Chunmei Gong, Justyna Malecka, Elisa Tonelli, Armando A. Genazzani, Laura Tapella, Anna Maria Eleuteri, Dmitry Lim, Laura Bonfili   +8 more
openalex   +1 more source

Reticulon-1A mediates diabetic kidney disease progression through endoplasmic reticulum-mitochondrial contacts in tubular epithelial cells

, 2022
Yifan Xie, E Jing, Hong Cai, Fang Zhong, Wenzhen Xiao, Ronald E. Gordon, Lois Wang, Ya-Li Zheng, Aihua Zhang, Kyung Lee, John Cijiang He   +10 more
openalex   +2 more sources

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Examining saliva proteomic dynamics in mitochondrial diseases from a perspective of intrinsic health. [PDF]

Sci Rep
Zhao J, Xu B, Huang T, Honfo SH, Trumpff C, Picard M, Cohen AA, Liu M.   +7 more
europepmc   +1 more source

Mutations in COX7B Cause Microphthalmia with Linear Skin Lesions, an Unconventional Mitochondrial Disease [PDF]

, 2012
Alessia Indrieri, Vanessa A. van Rahden, Valeria Tiranti, Manuela Morleo, Daniela Iaconis, Roberta Tammaro, Ilaria D’Amato, Iván Conte, Isabelle Maystadt, Stephanie Demuth, Alex Zvulunov, Kerstin Kutsche, Massimo Zeviani, Brunella Franco   +13 more
openalex   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source