Results 241 to 250 of about 10,050,443 (381)

Fragile T-stem in Disease-associated Human Mitochondrial tRNA Sensitizes Structure to Local and Distant Mutations [PDF]

, 2001
Shana O. Kelley, Sergey V. Steinberg, Paul Schimmel   +2 more
openalex   +1 more source

Mitochondrial and metabolic dysfunction in ageing and age-related diseases

Nature Reviews Endocrinology, 2022
J. Amorim, G. Coppotelli, A. Rolo, C. Palmeira, J. M. Ross, D. Sinclair   +5 more
semanticscholar   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

Adrenal Dysfunction in Mitochondrial Diseases. [PDF]

Int J Mol Sci, 2023
Corkery-Hayward M, Metherell LA.
europepmc   +1 more source

Biomarkers of DNA damage in patients with end‐stage renal disease: mitochondrial DNA mutation in hair follicles [PDF]

, 2001
Chin‐San Liu, Lie‐Yon Ko, Paik‐Seong Lim, Shu‐Huei Kao, Yau‐Huei Wei   +4 more
openalex   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Expanding the genetic spectrum of mitochondrial diseases in Tunisia: novel variants revealed by whole-exome sequencing. [PDF]

Front Genet, 2023
Gouiza I, Hechmi M, Zioudi A, Dallali H, Kheriji N, Charif M, Le Mao M, Galai S, Kraoua L, Ben Youssef-Turki I, Kraoua I, Lenaers G, Kefi R.   +12 more
europepmc   +1 more source

Hodgkin disease‐derived cell lines expressing ubiquitous mitochondrial creatine kinase show growth inhibition by cyclocreatine treatment independent of apoptosis [PDF]

, 2001
Martin Kornacker, Uwe Schlattner, Theo Wallimann, Micheal R. Verneris, Robert S. Negrin, Birgit Kornacker, Andrea Staratschek‐Jox, Volker Diehl, Juergen Wolf   +8 more
openalex   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Endocrine manifestations and long-term outcomes of patients with mitochondrial diseases. [PDF]

Orphanet J Rare Dis
Kim JH, Kim D, Hwang S, Kim GH, Lee BH, Yoo HW, Choi JH.   +6 more
europepmc   +1 more source