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Platyzoan mitochondrial genomes
Molecular Phylogenetics and Evolution, 2013Platyzoa is a putative lophotrochozoan (spiralian) subtaxon within the protostome clade of Metazoa, comprising a range of biologically diverse, mostly small worm-shaped animals. The monophyly of Platyzoa, the relationships between the putative subgroups Platyhelminthes, Gastrotricha and Gnathifera (the latter comprising at least Gnathostomulida ...
Holger Herlyn +3 more
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Mitochondrial fusion and inheritance of the mitochondrial genome
Journal of Plant Research, 2010Although maternal or uniparental inheritance of mitochondrial genomes is a general rule, biparental inheritance is sometimes observed in protists and fungi,including yeasts. In yeast, recombination occurs between the mitochondrial genomes inherited from both parents.Mitochondrial fusion observed in yeast zygotes is thought to set up a space for DNA ...
Kenta Onoue +2 more
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The mitochondrial genome and mitochondrial muscle disorders
Current Opinion in Pharmacology, 2001Mitochondrial disorders represent a multitude of clinically heterogeneous diseases in which the genetic abnormality can involve either a mitochondrial or nuclear gene. In addition to inherited defects, somatic mitochondrial DNA mutations have been implicated in the pathogenesis of neurodegenerative disease, cancer and the ageing process.
Andrew M. Schaefer +2 more
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The Mitochondrial Genome And Human Mitochondrial Diseases
Journal of the Peripheral Nervous System, 2002To date, more than 100 point mutations and several hundreds of structural rearrangements of mitochondrial DNA (mtDNA) are known too be connected with characteristic neuromuscular and other mitochondrial syndromes varying from those causing death at the neonatal stage to diseases with late ages of onset. The immediate cause of mitochondrial disorders is
Rem I. Sukernik +8 more
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Mitochondrial Genomes of the Ciliates
1992Publisher Summary This chapter describes the mithochondrial genome of ciliates, with emphasis on Paramecium and Tetrahymena . Both Paramecium and Tetrahymena have linear genomes with unique replicative pathways. The mitochondrial genome of Paramecium aurelia is a linear duplex.
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Evidence that the mitochondrial genome is the thrifty genome
Diabetes Research and Clinical Practice, 1999Although mitochondrial DNA (mtDNA) abnormalities are known to cause insulin deficiency, insulin resistance and diabetes mellitus, it's quantitative aspect was not addressed well. In this review, mitochondrial genome hypothesis of thrifty phenomenon is proposed, based on the data and review of literatures. From a population based epidemiologic study, it
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Comparison of mitochondrial genomes of bivalves
Hereditas (Beijing), 2009The structure and organization of mitochondrial genomes of 14 marine bivalves and two freshwater bivalves were analyzed using comparative genomics and bioinformatics methods. The results showed that the organization and gene order of the mitochondrial genomes of these bivalve species studied were different from each other.
Xianggang Gao +5 more
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The mitochondrial genome in aging and senescence
Ageing Research Reviews, 2014Aging is characterized by a progressive decline in organism functions due to the impairment of all organs. The deterioration of both proliferative tissues in liver, skin and the vascular system, as well as of largely post-mitotic organs, such as the heart and brain could be attributed at least in part to cell senescence.
A. Lauri, G. Pompilio, M. C. Capogrossi
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The Mitochondrial Genome in Embryo Technologies
Reproduction in Domestic Animals, 2003ContentsThe mammalian mitochondrial genome encodes for 37 genes which are involved in a broad range of cellular functions. The mitochondrial DNA (mtDNA) molecule is commonly assumed to be inherited through oocyte cytoplasm in a clonal manner, and apparently species‐specific mechanisms have evolved to eliminate the contribution of sperm mitochondria ...
Hiendleder, S., Wolf, E.
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Organization and expression of the mammalian mitochondrial genome
Nature reviews genetics, 2022O. Rackham, A. Filipovska
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