Results 81 to 90 of about 802,688 (257)
Contact sites between inner and outer membranes [PDF]
Contact sites between both mitochondrial membranes play a predominant role in the transport of nuclear-coded precursor proteins into mitochondria. The characterization of contact sites was greatly advanced by the reversible accumulation of precursor ...
Attardi+30 more
core +1 more source
Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale
Mitochondria perform central functions in cellular bioenergetics, metabolism, and signaling, and their dysfunction has been linked to numerous diseases.
Marcel Morgenstern+17 more
doaj +1 more source
Different Transport Pathways of Individual Precursor Proteins in Mitochondria [PDF]
Transport of mitochondrial precursor proteins into mitochondria of Neurospora crassa was studied in a cellfree reconstituted system. Precursors were synthesized in a reticulocyte lysate programmed with Neurospora mRNA and transported into isolated ...
Allen E. H.+31 more
core +1 more source
Mitochondrial Oxidative Damage in Chicken Skeletal Muscle Induced by Acute Heat Stress
Mitochondria have long been known to play a critical role in maintaining bioenergetic status under physiological conditions. Our previous studies have shown that acute heat stress increases production of mitochondrial reactive oxygen species (ROS) in ...
Ahmad Mujahid+6 more
doaj +1 more source
The selectivity filter of the mitochondrial protein import machinery
Background The uptake of newly synthesized nuclear-encoded mitochondrial proteins from the cytosol is mediated by a complex of mitochondrial outer membrane proteins comprising a central pore-forming component and associated receptor proteins.
Sebastian Kreimendahl+4 more
doaj +1 more source
The processing peptidase of yeast mitochondria [PDF]
Two proteins co-operate in the proteolytic cleavage of mitochondrial precursor proteins: the mitochondrial processing peptidase (MPP) and the processing enhancing protein (PEP).
Cheng, Ming Yuan+5 more
core
Acetylation of Mitochondrial Proteins in the Heart: The Role of SIRT3
A growing number of studies have demonstrated the role of post-translational modifications of proteins, particularly acetylation, in human diseases including neurodegenerative and cardiovascular diseases, diabetes, cancer, and in aging.
Rebecca M. Parodi-Rullán+2 more
doaj +1 more source
Mitochondrial protein import [PDF]
The transport of nuclear-encoded proteins from the cytosol into mitochondria is mediated by targeting (signal) sequences present on precursor forms.
Neupert, Walter, Schwarz, Elisabeth
core +1 more source
Quantification of DNA Products Using Ion-Pair Reverse Phase Liquid Chromatography [PDF]
The transcription of DNA via RNA polymerases is a fundamental process in cellular systems. In eukaryotic cells, we observe transcription in the nucleus (via genomic DNA) as well as in the mitochondria (via mitochondrial DNA).
Bestwick, Megan, Wienkers, Henry
core +1 more source
Mdj1p, a novel chaperone of the DnaJ family, is involved in mitochondrial biogenesis and protein folding [PDF]
Mdj1p, a novel member of the DnaJ family, is a heat shock protein that is associated with the inner membrane of mitochondria of Saccharomyces cerevisiae.
Amin+63 more
core +1 more source