Results 21 to 30 of about 18,846,273 (226)

Tailoring Targeted Therapy to Individual Patients: Lessons to be Learnt from the Development of Mitomycin C [PDF]

open access: yes, 2007
The modern era of targeted therapeutics offers the potential to tailor therapy to individual patients whose tumours express a specific target. Previous attempts to forecast tumour response to conventional chemotherapeutics based on similar principles ...
Phillips, Roger M, Volpato, Milene
core   +3 more sources

Applications of Mitomycin C in Cornea and External Disease [PDF]

open access: yes, 2023
Isolated from Streptomyces caespitosus, mitomycin C (MMC) has various applications in the management of corneal and external disease due to its ability to modulate cellular proliferation.
Marcos A. Crespo   +2 more
core   +1 more source

Two routes of administration of mitomycin C in a trabeculectomy

open access: yesIndian Journal of Ophthalmology, 2023
Background: The introduction of mitomycin C (MMC) as an adjunct to trabeculectomy was a major advance in the ability to improve the Intra ocular pressure lowering efficiency of the procedure.
Manju Pillai   +3 more
doaj   +1 more source

The Possible Role of the Long Non-coding RNA NORAD in Mitomycin C-Related Chemoresistance

open access: yesNamık Kemal Tıp Dergisi, 2022
Aim:Non-coding ribonucleic acid (RNA) activated by deoxyribonucleic acid (DNA) damage (NORAD) is a long non-coding RNA activated during DNA damage response.
İbrahim BOZGEYİK
doaj   +1 more source

Efficacy of mitomycin C in modified transcanalicular diode laser dacryocystorhinostomy [PDF]

open access: yesRevista Brasileira de Oftalmologia, 2022
Objective: To evaluate the efficacy of mitomycin C in anatomical and functional success after modified transcanalicular diode laser dacryocystorhinostomy. Methods: A prospective, double-blinded, randomized placebo-controlled study compared the effect of
Eduardo Damous Feijó   +5 more
doaj   +1 more source

Intraoperative injection versus sponge-applied mitomycin C during trabeculectomy: One-year study

open access: yesIndian Journal of Ophthalmology, 2020
Purpose: To determine the safety and efficacy of mitomycin C (MMC) injection versus sponge during trabeculectomy. Methods: It is a prospective analysis of patients who underwent trabeculectomy with MMC and followed up for 1 year, divided into two groups,
Devendra Maheshwari   +3 more
doaj   +1 more source

Mitomycin C induces apoptosis in human epidural scar fibroblasts after surgical decompression for spinal cord injury

open access: yesNeural Regeneration Research, 2017
Numerous studies have shown that topical application of mitomycin C after surgical decompression effectively reduces scar adhesion. However, the underlying mechanisms remain unclear.
Tao Sui   +5 more
doaj   +1 more source

Inadvertent filtering bleb due to extracapsular cataract extraction wound reopening after mitomycin C use: a case report

open access: yesJournal of Medical Case Reports, 2023
Background  Mitomycin C has been used adjunctively in various procedures, including pterygium excision. Delayed wound healing, the long-term complication of mitomycin C, can occur several years later and may rarely cause a subsequent inadvertent ...
Phit Upaphong   +2 more
doaj   +1 more source

A new concurrent chemotherapy with vinorelbine and mitomycin C in combination with radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck [PDF]

open access: yes, 2005
Objective: The purpose of this pilot study was to evaluate the feasibility and toxicity of concurrent chemotherapy with vinorelbine and mitomycin C in combination with accelerated radiotherapy (RT) in patients with locally advanced cancer of the head and
Wilkowski, R.   +5 more
core   +1 more source

Efficacy of preoperative injection versus intraoperative application of mitomycin in recurrent pterygium surgery

open access: yesIndian Journal of Ophthalmology, 2012
Purpose: To determine the efficacy of preoperative subconjunctival injection of mitomycin C a day before surgery in the management of recurrent pterygium. Materials and Methods: Randomized comparative case series. Fifty eyes with recurrent pterygium were
Khaled S Zaky, Yasser M Khalifa
doaj   +1 more source

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