Results 71 to 80 of about 47,786 (197)
A randomized placebo controlled trial of Mitomycin - C in surgical outcome of primary endoscopic dacryocystorhinostomy [PDF]
Al Ameen Journal of Medical Sciences, 2013 Objective: To compare the patency of the stoma and relief of epiphora after endoscopic dacrocystorjinostomy (EnDCR) surgery with Mitomycin C and Placebo in cases of chronic dacrocystitis secondary to primary post saccal stenosis.
A.S. Harugop +6 more
doaj
Cell Proliferation, EarlyView.Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu +4 more
wiley +1 more source
Surgical excision of melanomas in the anal region and reconstruction of the anus in 11 horses
Equine Veterinary Education, EarlyView.Summary This case report describes the surgical excision of large perianal and perineal melanomas, and reconstruction of the anus in 11 grey horses. Four horses had a history of painful defaecation or urination due to extensive tumours. Seven horses had no clinical signs at the time of admission but had rapidly growing nodules around the anus with ...
F. Somm, A. E. Fürst, M. A. Jackson
wiley +1 more source
International Medical Case Reports Journal, 2021 Majid Moshirfar,1– 3 William B West Jr,4 Dallin C Milner,5 Shannon E McCabe,1 Yasmyne C Ronquillo,1 Phillip C Hoopes1 1Hoopes Vision Research Center, Hoopes Vision, Draper, UT, 84020, USA; 2John A. Moran Eye Center, Department of Ophthalmology and Visual
Moshirfar M +5 more
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Corneal Melt with Perforation Following Topical Mitomycin-C Application in Pterygium Excision
Delhi Journal of Ophthalmology, 2019 We report a case of corneal melt with perforation due to Mitomycin-C application during Pterygium excision. A 50-year-old male presented with sudden gross diminution of vision and pain in the left eye since one day.
Shashidhar Banigallapati, Akhil Bevara
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Limited roles of the miR‐17‐92 cluster in the regulation of T‐cell apoptosis
The FEBS Journal, EarlyView.The pro‐apoptotic protein BIM shapes T‐cell survival and function, but how it is regulated remains unclear. In a mouse model lacking direct miR‐17‐92:Bim interactions, we observed a moderate reduction in Th17 CD4+ T cells. BIM levels were modestly increased in double‐positive thymocytes and naive CD8+ T cells, but this did not affect overall T‐cell ...
Katharina Hoppe +7 more
wiley +1 more source
GCN2 in proteostasis: structural logic, signalling networks and disease
The FEBS Journal, EarlyView.Threats to protein synthesis activate the kinase GCN2, initiating the integrated stress response (ISR). GCN2 is triggered by stalled ribosomes and uncharged tRNAs, which accumulate when amino acids are scarce. The ISR adjusts cellular physiology by promoting redox balance, protein quality control, and mitochondrial optimisation.
JiaYi Zhu, Stefan J. Marciniak
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Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review
Photochemistry and Photobiology, EarlyView.Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima +6 more
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Southwest Respiratory and Critical Care Chronicles, 2015 Tracheal stenosis is an uncommon but known complication of endotracheal intubation and tracheostomy. Surgery is currently the definitive treatment for tracheal stenosis but carries a significantly higher risk for adverse events as it often involves ...
Audra Fuller +3 more
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Photochemistry and Photobiology, EarlyView.FIR irradiation enhances the physical association between Akt and PP2Ac in VSMCs, independent of the hyperthermal effect of FIR rays. The increased binding between Akt and PP2Ac induced by FIR irradiation facilitates the dephosphorylation of Akt at Ser473.
Na‐Young Lee +5 more
wiley +1 more source