Results 31 to 40 of about 960 (156)

Mitomycin alkaloids: synthetic studies [PDF]

open access: yes, 2009
2009 Spring.Includes bibliographical references.Documented herein are efforts towards the first asymmetric total synthesis of the mitomycin family of natural products.
Elliott, C. Michael, committee member   +5 more
core  

Distinct Patterns of Colorectal Peritoneal Metastases at Initial and Repeat Cytoreductive Surgery

open access: yesWorld Journal of Surgery, EarlyView.
Colorectal cancer rates are continually increasing in Western countries exceeding over 3 million new cases annually. Hematogenous spread to the liver is the most common metastatic route, followed by transcoelomic dissemination to the peritoneum. Colorectal peritoneal metastases (CRPM) affect 5%–8% at the time of initial diagnosis and a further 10%–20 ...
Mina Sarofim, David L. Morris
wiley   +1 more source

Enterococcus faecalis and Endodontic Treatment Failure: A Qualitative Systematic Review of Its Role and Elimination Strategies

open access: yesAustralian Endodontic Journal, EarlyView.
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima   +1 more
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick   +7 more
wiley   +1 more source

Efforts toward the total synthesis of mitomycins

open access: yes, 2009
This thesis describes our efforts toward the total synthesis of mitomycins. The centerpiece of our route to the target molecule is a homo-Brook mediated aziridine fragmentation, developed in our laboratory. The aziridine moiety of the target molecule was
Vialettes, Anne
core  

The efficacy and safety of reducing intraocular pressure to single‐digit levels in Normal‐tension glaucoma: A systematic review and meta‐analysis

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose This systematic review and meta‐analysis aim to evaluate the efficacy and safety of further lowering intraocular pressure (IOP) to single‐digit levels in treated patients with progressive normal‐tension glaucoma (NTG). Methods A literature search was conducted in MEDLINE (via PubMed), Scopus and Web of Science. We selected studies that
Beatriz Araújo‐Azevedo   +2 more
wiley   +1 more source

A prospective randomised comparison of two different stenting sutures when using the Baerveldt 101–350 aqueous shunt – Lab transition to clinical process

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose The Baerveldt glaucoma drainage implant (BGI 101–350) is one of the most effective treatment options for managing refractory glaucoma. To mitigate early hypotony in non‐valved implants, intraluminal occluding sutures (IOSs) are commonly used.
Evripidis Sykakis   +7 more
wiley   +1 more source

C(7)-Substituted Diaminomitomycins:  Synthesis, Structure, and Chemical Reactivity

open access: yes, 2016
Five mitomycins (23−27) were prepared to determine if an appended C(7) diamine substituent would promote C(1) nucleophilic substitution transformations by covalent modification of the C(8) quinone group.
Harold Kohn (1333722)   +1 more
core   +1 more source

Vision‐related quality of life following trabeculectomy versus Baerveldt glaucoma implant: Five‐year results from a randomized clinical trial

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To assess the vision‐related quality of life (VRQoL) in glaucoma patients over 5 years after primary Baerveldt glaucoma implant (BGI) or trabeculectomy (TE) using a secondary analysis of a randomized clinical trial. Methods Patients were randomized to undergo TE or receive a BGI.
Ionela Popescu‐Giovanitsas   +4 more
wiley   +1 more source

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