Results 121 to 130 of about 163,907 (337)

La morfología de la línea de esmalte en los molares de los roedores muroideos es explicada mediante una red hexagonal

open access: yesEstudios Geologicos, 2011
La línea de esmalte observada en la corona de los roedores muroideos tiene formas geométricas que coinciden exactamente con una red plana triangular equilateral. Esta conclusión ayuda a explicar el modelo dental de los muroideos con una nueva perspectiva
A. Ruiz Bustos
doaj   +1 more source

Getting In and Out of Mitosis [PDF]

open access: yesRambam Maimonides Medical Journal, 2011
(Excerpt) Mitosis is the process of one cell dividing into two replicate cells. This process is a universal one, occurring throughout the phyla. Mitosis is a fundamental process. Without it, life ceases to exist.
openaire   +4 more sources

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

open access: yesAdvanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang   +10 more
wiley   +1 more source

A Unified Framework for Tumor Proliferation Score Prediction in Breast Histopathology [PDF]

open access: yesarXiv, 2016
We present a unified framework to predict tumor proliferation scores from breast histopathology whole slide images. Our system offers a fully automated solution to predicting both a molecular data-based, and a mitosis counting-based tumor proliferation score.
arxiv  

Mitosis: Introduction [PDF]

open access: yesCell Cycle, 2002
Even before biochemical and genetic approaches were employed, many researchers were captivated and astounded by mitosis. Cell biologists have been enthralled by its sheer beauty for more than a century (Fig. 1). Yanagida, who probably contributed more to the genetic dissection of mitotic processes than any other scientist, described it as a "cellular ...
openaire   +3 more sources

Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure‐Based Virtual Screening

open access: yesAdvanced Science, EarlyView.
Pancreatic cancer is a highly aggressive malignancy with limited treatment options. CLK4 regulates alternative splicing, contributing to cancer progression. This study establishes a computational model to identify CLK4 inhibitors, leading to compound 150441 (IC50: 21.4 nm).
Chun‐Lin Yang   +13 more
wiley   +1 more source

Phosphorylated ERK5/BMK1 transiently accumulates within division spindles in mouse oocytes and preimplantation embryos

open access: yesFolia Histochemica et Cytobiologica, 2011
MAP kinases of the ERK family play important roles in oocyte maturation, fertilization, and early embryo development. The role of the signaling pathway involving ERK5 MAP kinase during meiotic and mitotic M-phase of the cell cycle is not well known. Here,
Maria A. Ciemerych   +3 more
doaj   +1 more source

Aqueous Two‐Phase Submicron Droplets Catalyze DNA Nanostructure Assembly for Confined Fluorescent Biosensing

open access: yesAdvanced Science, EarlyView.
Submicron droplets, formed by a polyethyleneglycol (PEG)/dextran aqueous two‐phase system·(ATPS), can act as catalytic centers that concentrate DNA and accelerate assembly kinetic in crowded environments. It highlights a cooperative mechanism wherein global crowding from PEG induces an excluded volume effect, while local crowding from dextran provides ...
Xiaoman Duan   +5 more
wiley   +1 more source

Inactivation of RB1, CDKN2A, and TP53 have distinct effects on genomic stability at side‐by‐side comparison in karyotypically normal cells

open access: yesGenes, Chromosomes and Cancer, Volume 62, Issue 2, Page 93-100, February 2023., 2023
Abstract Chromosomal instability is a common feature in malignant tumors. Previous studies have indicated that inactivation of the classical tumor suppressor genes RB1, CDKN2A, and TP53 may contribute to chromosomal aberrations in cancer by disrupting different aspects of the cell cycle and DNA damage checkpoint machinery.
Natalie Andersson   +6 more
wiley   +1 more source

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