Results 211 to 220 of about 163,907 (337)

The Impact of the Rs1044457 Polymorphism in the CMPK1 Gene on the Response Rate to Gemcitabine‐Based Chemotherapy in Metastatic NSCLC Patients

open access: yesAdvanced Genetics, EarlyView.
Lung cancer is the leading cause of cancer‐related mortality worldwide. Among its types, non‐small cell lung cancer (NSCLC) accounts for the majority of cases. This study focuses on investigating genetic mutations that may influence the response to gemcitabine, a chemotherapy drug commonly used to treat this condition.
Ghassan Saod Saleh   +3 more
wiley   +1 more source

MDM2 functions as a timer reporting the length of mitosis. [PDF]

open access: yesNat Cell Biol
Fulcher LJ   +4 more
europepmc   +1 more source

Alternative MYB Promoter Activity Is a Potential Prognostic Biomarker in Head and Neck Adenoid Cystic Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is an aggressive therapy‐resistant head and neck cancer with a high frequency of local recurrences and distant metastases. Activation of the MYB gene, encoding an oncogenic master transcription factor, is the key genomic hallmark of ACC and a potential therapeutic target. Here, we have investigated the
Fredrik Jäwert   +5 more
wiley   +1 more source

PICH impacts the spindle assembly checkpoint via its DNA translocase and SUMO-interaction activities. [PDF]

open access: yesLife Sci Alliance
Lama B   +11 more
europepmc   +1 more source

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