Results 321 to 330 of about 379,827 (391)

Decoding the Role of CDCA Genes in Breast Cancer Progression: Insights From in Silico and Functional Assay

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Investigating the diagnostic potential and functional role of CDCA genes in breast cancer. ABSTRACT Background The cell division cycle‐associated (CDCA) genes regulate key cellular processes like cell cycle progression and division. This study evaluates the diagnostic and clinical relevance of CDCA genes in breast cancer.
Yongsheng Zhao, Xiaocha Ma, Jun Zhou
wiley   +1 more source

Centromere Protein F in Tumor Biology: Cancer's Achilles Heel. [PDF]

Cancer Med
Wan Z, Wen M, Zheng C, Sun Y, Zhou Y, Tian Y, Xin S, Wang X, Ji X, Yang J, Xiong Y, Han Y.   +11 more
europepmc   +1 more source

Rapid detection of mouse spermatogenic defects by testicular cellular composition analysis via enhanced deep learning model

Andrology, EarlyView.
Abstract Background Histological analysis of the testicular sections is paramount in infertility research but tedious and often requires months of training and practice. Objectives Establish an expeditious histopathological analysis of mutant mice testicular sections stained with commonly available hematoxylin and eosin (H&E) via enhanced deep learning
Nianfei Ao, Min Zang, Yue Lu, Yiping Jiao, Haoda Lu, Chengfei Cai, Xiangxue Wang, Xin Li, Minge Xie, Tingting Zhao, Jun Xu, Eugene Yujun Xu   +11 more
wiley   +1 more source

Dawning aurora: TPXL3 activates α-Aurora kinase and regulates mitotic spindle morphogenesis. [PDF]

Plant Cell
Kolli R.
europepmc   +1 more source

ZIP10 as a potential therapeutic target in acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Increased intracellular zinc levels in acute myeloid leukaemia blasts with upregulated expression of zinc influx transporters ZIP6 and ZIP10. Targeting ZIP10 with a surface antibody represents a potential therapeutic strategy. Created in BioRender. Rolles, B. (2025) https://BioRender.com/bwrtof1.
Benjamin Rolles, Nicolas Chatain, Richard Görg, Margherita Vieri, Nora Tillmann‐Tröster, Marcel G. Bourgeois, Deborah Christen, Jeanette Walter, Addison C. Hillerbrand, Kyle A. Romine, Kathryn M. Taylor, Jens Bertram, Edgar Jost, Steffen Koschmieder, Fabian Beier, Maximilian Stahl, Tim H. Brümmendorf, Lothar Rink, Inga Wessels   +18 more
wiley   +1 more source

SART1 uniquely localizes to spindle poles forming a SART1 cap and promotes spindle pole assembly. [PDF]

J Biol Chem
Yokoyama H, Moreno-Andrés D, Takizawa K, Chu Z, Scheufen A, Funabashi T, Ma J, Antonin W, Gruss OJ, Haramoto Y.   +9 more
europepmc   +1 more source

Beyond synapses: cytoplasmic connections in brain function and evolution

Biological Reviews, EarlyView.
ABSTRACT Following Ramón y Cajal's groundbreaking contributions to the identification of synapses, research in neuroscience predominantly focused on their pivotal role in neural communication (the neuron doctrine), overlooking an intriguing possibility suggested by Golgi of non‐synaptic interactions among neural cells.
Malalaniaina Rakotobe, Chiara Zurzolo
wiley   +1 more source

Probing centromere-kinetochore core complex CENP-L/M assembly using cenpemlin. [PDF]

J Mol Cell Biol
Durojaye OA, Yang F, Gao X, Aikhionbare F, Zhang L, Liu X, Yao X.   +6 more
europepmc   +1 more source

Nuclear destabilisation – a possible genesis of cancer?

Biological Reviews, EarlyView.
ABSTRACT This review examines the increasingly prominent role of mechanics within cancer formation and progression. The extremely varied and contradictory genetic landscape of cancer is in stark contrast to the seemingly universal mechanical characteristics of cancer cells and their tumour microenvironment, and mechanics may be a principal unifying ...
Daniel D. Scott, Francesco Bettariga, Marco Ventin, Chris Bishop, Britta Stordal   +4 more
wiley   +1 more source

Nondisruptive inducible labeling of ER-membrane contact sites using the Lamin B receptor. [PDF]

PLoS Biol
Downie L, Ferrandiz N, Courthold E, Jones M, Royle SJ.   +4 more
europepmc   +1 more source