Results 321 to 330 of about 386,071 (373)

A time-resolved atlas of histone modifications during mitotic entry

Kochanova NY, Borsò M, Deb M, Webb S, Ustun I, Samejima K, Forne I, Samejima I, Xie L, Paulson JR, Imhof A, Earnshaw WC.   +11 more
europepmc   +1 more source

Condensin chromatin association is regulated by SMC head and hinge engagement and phosphorylation

Miles CA, Yu M, Minchell NE, Schalbetter SA, Oliver AW, Sweet SM, Baxter J.   +6 more
europepmc   +1 more source

The mitotic stopwatch limits the proliferation of whole genome doubled cells

Allan L, Foy R, Keli M, Saurin A.
europepmc   +1 more source

Actin cables and comet tails organize mitochondrial networks in mitosis

Nature, 2021
Symmetric cell division requires the even partitioning of genetic information and cytoplasmic contents between daughter cells. Whereas the mechanisms coordinating the segregation of the genome are well known, the processes that ensure organelle ...
Andrew S Moore, Stephen M Coscia, Cory L Simpson   +2 more
exaly   +2 more sources

Phosphorylation and chromatin tethering prevent cGAS activation during mitosis

Science, 2021
Keeping cGAS silent Cells detect microbial and self-DNA in the cytosol as a danger signal that triggers immune and inflammatory responses. Paradoxically, a large fraction of a DNA-sensing enzyme called cGAS is tightly associated with the chromatin ...
Tuo Li, Tuozhi Huang, Mingjian Du
exaly   +2 more sources

Chromatin structure dynamics during the mitosis-to-G1 phase transition

Nature, 2019
Features of higher-order chromatin organization—such as A/B compartments, topologically associating domains and chromatin loops—are temporarily disrupted during mitosis1,2.
Haoyue Zhang, Thomas G Gilgenast, Katelyn R Titus   +2 more
exaly   +2 more sources

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Kinase-controlled phase transition of membraneless organelles in mitosis

Nature, 2018
Jia-Xuan Chen, Matthias Selbach, Lucas Pelkmans   +2 more
exaly   +2 more sources

DNA breaks and chromosome pulverization from errors in mitosis

Nature, 2012
The involvement of whole-chromosome aneuploidy in tumorigenesis is the subject of debate, in large part because of the lack of insight into underlying mechanisms. Here we identify a mechanism by which errors in mitotic chromosome segregation generate DNA
Karen Crasta, Neil J Ganem, Luigi Nezi
exaly   +2 more sources

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

Nature Reviews Molecular Cell Biology, 2012
Mar Carmena, Hironori Funabiki
exaly   +2 more sources

A changing paradigm of transcriptional memory propagation through mitosis

Nature Reviews Molecular Cell Biology, 2018
Katherine C Palozola, Jonathan Lerner, Kenneth S Zaret   +2 more
exaly   +2 more sources