Results 321 to 330 of about 380,556 (390)

Enfortumab Vedotin‐Related Skin Toxicities: Insights From Clinical and Histopathological Analysis

The Journal of Dermatology, EarlyView.
ABSTRACT Enfortumab vedotin (EV), targeting Nectin‐4, is effective in advanced urothelial carcinoma but frequently causes skin toxicities. This study examined the possible contribution of prior immune checkpoint inhibitor (ICI) therapy and higher EV doses to EV‐related skin toxicity (EVST) development.
Yuki Kuma, Makiko Kido‐Nakahara, Yoko Kuba‐Fuyuno, Takashi Matsumoto, Yoshinao Oda, Masatoshi Eto, Takeshi Nakahara   +6 more
wiley   +1 more source

Hypothesis that ancestral eukaryotes sexually proliferated without kinetochores or mitosis.

J Cell Sci
Akiyoshi B.
europepmc   +1 more source

The localisation and stability of the CENP-F protein are regulated by importin beta and microtubules in mitotic cells. [PDF]

Sci Rep
Altieri L, Damizia M, Rovella P, Costanzo V, Mancini M, Di Micco P, Marzi M, Trisciuoglio D, Morea V, Lavia P.   +9 more
europepmc   +1 more source

Differential gene expression in Chorthippus parallelus (Zetterstedt, 1821) (Orthoptera: Acrididae: Gomphocerinae) induced by Wolbachia infection

Insect Science, EarlyView.
Distinct lineages of the grasshopper Chorthippus parallelus (Orthoptera: Acrididae) form a well‐known hybrid zone (HZ) in the Pyrenees mountain range; the Iberian endemism C. p. erythropus (Cpe) and the subspecies C. p. parallelus, (Cpp) widely distributed throughout the rest of Europe. Both subspecies differ in diverse traits, including the strains of
Patricia Jiménez‐Florido, Mónica Aquilino, David Buckley, José L. Bella, Rosario Planelló   +4 more
wiley   +1 more source

Embryonic Development of Caenorhabditis elegans Sense Organs. [PDF]

J Comp Neurol
Wexler LR, Kolotuev I, Heiman MG.
europepmc   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Phosphatase regulation in cell division: With emphasis on PP2A-B56. [PDF]

Mol Cells
Oh J, Park Y, Park S, Woo OG, Lee JH, Lee JS, Kim T.   +6 more
europepmc   +1 more source

Jasmonates enhance plants tolerance grown in Cd‐contaminated environments: A comprehensive overview

Annals of Applied Biology, EarlyView.
Jasmonates (JAs) enhance plant tolerance to cadmium (Cd) stress by activating antioxidant defences but may reduce Cd uptake, limiting their effectiveness for phytoremediation. This review compiles studies that evaluated the effects of JA application on plants grown in Cd‐contaminated environments. Abstract Cadmium (Cd) is a toxic heavy metal and one of
Raja Yamma Rodrigues Souza, Cristiano Soares, Daniel Baron   +2 more
wiley   +1 more source

Phosphorylation of CENP-C by PLK1 ensures accurate chromosome congression during mitosis. [PDF]

J Mol Cell Biol
He S, Wang C, Shao H, Hu C, Hu R, Liu R, Tao C, Wang C, Fu C, Liu X, Yao X, Zhang L.   +11 more
europepmc   +1 more source

Prematurely Aged Human Microglia Exhibit Impaired Stress Response and Defective Nucleocytoplasmic Shuttling of ALS Associated FUS

Aging Cell, EarlyView.
We developed a human microglia aging model by doxycycline‐induced GFP‐progerin expression, which offers a valuable tool to study human microglial aging and its contribution to neurodegeneration. Induced HMC3‐Progerin cells exhibited increased age markers as well as transcriptomic alterations, including an age‐associated transcriptomic shift and ...
Christiane Hartmann, Christina Haß, Muriel Knobloch, Israel Barrantes, Laura Fumagalli, Jessie Premereur, Franz Markert, Maite Peters, Georgia Koromila, Alexander Hartmann, Kathrin Jäger, Jette Abel, Renzo Mancuso, Alexander Storch, Michael Walter, Georg Fuellen, Andreas Hermann   +16 more
wiley   +1 more source