Results 111 to 120 of about 62,233 (223)

Unveiling New Insights: Reinterpreting DES Mutation, p.Arg383His, Through a Study of an Iranian Family With Isolated Hypertrophic Cardiomyopathy, Implication for Phenotype–Genotype Correlation Analysis

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi   +5 more
wiley   +1 more source

Evidence‐Based Nursing Management During Mavacamten Therapy in an 89‐Year‐Old Patient With Symptomatic Hypertrophic Obstructive Cardiomyopathy: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT In older patients receiving mavacamten, a reduction in NT‐proBNP levels may coexist with persistent severe LVOTO. Nurses should interpret this biomarker–echocardiography discordance as a safety signal and maintain structured cardiovascular surveillance rather than assuming treatment success based solely on biomarker improvement.
Feifei Wang
wiley   +1 more source

Impella‐Assisted High‐Risk Percutaneous Coronary Intervention in Cardiogenic Shock With Low‐Flow, Low‐Gradient Aortic Stenosis and Multivessel Coronary Artery Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Patients with cardiogenic shock, low‐flow, low‐gradient aortic stenosis, and multivessel coronary artery disease who are ineligible for surgery present a major therapeutic challenge. Percutaneous mechanical circulatory support may facilitate revascularization in this high‐risk population. A 69‐year‐old man presented after a mechanical fall and
Douni Roger   +3 more
wiley   +1 more source

Simultaneous Heart–Kidney Transplantation for Ebstein's Anomaly: A Viable Treatment Option in Latin America

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
Chest x‐ray showing a typical presentation of Ebstein anomaly with severe cardiomegaly and a prominent right atrium silhouette. ABSTRACT Simultaneous heart–kidney transplantation is a viable and effective treatment option for patients with congenital heart disease and advanced chronic kidney disease when both conditions threaten survival.
Edgar García‐Cruz   +12 more
wiley   +1 more source

Methodological Considerations on Pre‐Sport Cardiac Evaluation in Children: Detection of Risks Other Than Sudden Cardiac Death

open access: yes
Annals of Noninvasive Electrocardiology, Volume 31, Issue 5, September 2026.
Abdullah Aman   +2 more
wiley   +1 more source

A Rare Constellation of Peripartum Cardiomyopathy Manifesting With Multiple Thromboembolic Phenomena in a 15‐Year‐Old

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 15‐year‐old postpartum primipara presented at 19 days with aphasia, right hemiparesis, chest pain, and dyspnea. Diagnostics confirmed concurrent cardioembolic stroke and pulmonary embolism secondary to peripartum cardiomyopathy (ejection fraction 29%).
Reuben E. Mkama   +39 more
wiley   +1 more source

Impact of Severe Postoperative Multi‐Organ Dysfunction on Long‐Term Outcomes After Modified Morrow Surgery

open access: yesClinical Cardiology, Volume 49, Issue 8, August 2026.
This retrospective cohort study (n = 380) demonstrates that severe postoperative multi‐organ dysfunction (SOFA Maximum ≥ 11) is a strong independent predictor of long‐term adverse outcomes after modified Morrow surgery. Incorporating the SOFA score into postoperative assessments helps identify high‐risk hypertrophic obstructive cardiomyopathy patients ...
Tong Wang   +5 more
wiley   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 345-356, August 2026.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le   +8 more
wiley   +1 more source

Quantification of Tricuspid Valve Regurgitation With 2D and 4D‐Flow MRI: Comparison of Different Methods in Adult Patients With Ebstein's Anomaly

open access: yesJournal of Magnetic Resonance Imaging, Volume 64, Issue 2, Page 515-523, August 2026.
ABSTRACT Background Ebstein's anomaly (EA) is a congenital heart disorder involving tricuspid valve dysplasia and right heart abnormalities resulting in severe tricuspid regurgitation (TR). Multiple techniques assess regurgitation severity, but their correlation with EA severity markers remains unclear. Purpose To compare MRI techniques for quantifying
Eric Buffle   +8 more
wiley   +1 more source

Electrocardiographic Predictors of Cardiac Reverse Remodeling After Left Bundle Branch Area Pacing in Atrioventricular Block: Emphasis on Post‐Pacing QRS Duration

open access: yesJournal of Arrhythmia, Volume 42, Issue 4, August 2026.
In patients with atrioventricular block undergoing left bundle branch area pacing, shorter post‐pacing QRS duration was associated with cardiac reverse remodeling. Post‐pacing QRS duration may represent a simple and clinically applicable electrocardiographic marker for identifying patients more likely to achieve reverse remodeling.
Fahmi Nur Hidayatullah   +5 more
wiley   +1 more source

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