Results 121 to 130 of about 38,787 (289)

Pulmonary artery catheters or central venous catheters for cardiac surgery: the PUMA Pilot randomised clinical trial

Anaesthesia, EarlyView.
Summary Introduction Pulmonary artery catheters are used widely in cardiac surgery despite observed associations with worse outcomes and guidelines that recommend against their routine use. No adequately powered randomised trials are available. Methods The PUMA Pilot was a multicentre, randomised, parallel assignment, open‐label, pilot and feasibility ...
Luke A. Perry, Reny Segal, Marco Larobina, Rinaldo Bellomo, Julian A. Smith, Jesselyn Sin, Katrina Danial, Alistair R. D. McLean, Lisa Q. Rong, Mario Gaudino, Thomas Schwann, Marie Palumbo, Luke O'Halloran, Brian Chee, Jinesh Patel, Andrew Silvers, Jayme Bennetts, Silvana Marasco, Tim G. Coulson, Alistair Royse, Emily See, Lachlan F. Miles, on behalf of the ANZCA Clinical Trials Network   +22 more
wiley   +1 more source

Automated Annuloplasty with VirtuoSEW^® in microInvasive Mitral Valve Repair (μMVr)

Medical Sciences
Background/Objectives: Totally endoscopic mitral valve repair reduces surgical trauma and accelerates recovery but can be technically challenging, particularly for precise annuloplasty suturing.
Nermir Granov, Farhad Bakhtiary, Armin Šljivo, Jude S. Sauer   +3 more
doaj   +1 more source

Mitral Valve Repair: Five Techniques for 95% Repair

, 2019
Current American Heart Association/American College of Cardiology guidelines state that mitral valve repair for asymptomatic patients with preserved left ventricular function is reasonable when the likelihood of a successful and durable repair is greater
A. Marc Gillinov (6852603), Kevin Hodges (557116), Per Wierup (428719), Stephanie Mick (5166017), Daniel J. P. Burns (7140468)   +4 more
core   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Mitral regurgitation: challenges and solutions

, 2016
Julius I Ejiofor, Lawrence Cohn,† Tsuyoshi Kaneko Division of Cardiac Surgery, Brigham and Women’s Hospital, Boston, MA, USA †Lawrence Cohn passed away on January 9, 2016 Abstract: Since the first mitral valvuloplasty in 1923, the ...
Ejiofor JI, Kaneko T, Cohn L
core  

Compassionate use of the PASCAL transcatheter mitral valve repair system for patients with severe mitral regurgitation: a multicentre, prospective, observational, first-in-man study.

, 2017
BACKGROUND Severe mitral regurgitation is associated with impaired prognosis if left untreated. Using the devices currently available, transcatheter mitral valve repair (TMVr) remains challenging in complex anatomical situations.
Spargias, Konstantinos, Konstantinos Spargias, Florian Deuschl, Fam, Neil P, Webb, John, Edwards, Jeremy, Saibal Kar, Fabien Praz, Robert Schueler, John Webb, Kar, Saibal, Moody Makar, Michael Chrissoheris, Neil P Fam, Boone, Robert, Lutz Büllesfeld, Nickenig, Georg, Windecker, Stephan, Robert Moss, Praz, Fabien, Ted Feldman, Jeremy Edwards, Chrissoheris, Michael, Deuschl, Florian, Robert Boone, Büllesfeld, Lutz, Feldman, Ted, Aris Moschovitis, Schäfer, Ulrich, Stephan Windecker, Moschovitis, Aris, Makar, Moody, Moss, Robert, Georg Nickenig, Ulrich Schäfer, Schueler, Robert   +35 more
core   +1 more source

Cardiovascular outcomes for Australian women with rheumatic heart disease during pregnancy: A retrospective linked data analysis, 2002–2017

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This retrospective cohort study used linked data to measure the proportion of women with rheumatic heart disease (RHD) who experienced major adverse cardiovascular events (MACE) after 20 weeks of gestation. Before birth, 4.5% of women with initially uncomplicated RHD and 31.8% of women with initially complicated RHD experienced RHD‐MACE.
Ingrid Stacey, Mohammed Junaid, Holger W. Unger, Geraldine Vaughan, Ye’elah Berman, Vicki Wade, Lee Nedkoff, James Marangou, Judith M. Katzenellenbogen   +8 more
wiley   +1 more source

Comparison of Intraoperative Doppler Flow Measurements and Algorithmic Flow Estimations in Patients Undergoing Durable Left Ventricular Assist Device Implantation

Artificial Organs, EarlyView.
Direct intraoperative HeartMate 3 LVAD flow measurements using an ultrasonic probe revealed consistently higher values by approximately 0.5 L/min compared to device‐estimated flows. This discrepancy remained stable across pump speed settings, highlighting the importance of distinguishing measured from estimated flow in HeartMate 3 patients.
Gaik Nersesian, Anna Stegmann, Daniel Lewin, Yuriy Hrytsyna, Leonard Pitts, Julius Kaemmel, Marian Kukucka, Alexander Mladenow, Lisa Garczarek, Julia Stein, Friedrich Kaufmann, Volkmar Falk, Evgenij Potapov, Pia Lanmueller   +13 more
wiley   +1 more source

Transthoracic three-dimensional echocardiography for the assessment of straddling tricuspid or mitral valves

, 2000
Background The advent of 3D echocardiography has provided a technique which, potentially, could afford significant additional information over conventional cross-sectional echocardiography in the assessment of patients with straddling atrioventricular ...
Anderson, RH, Lincoln, C, Vogel, M, Ho, SY   +3 more
core  

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source