Results 81 to 90 of about 59,777 (302)

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

Degenerative mitral valve regurgitation: best practice revolution [PDF]

, 2017
Degenerative mitral valve disease often leads to leaflet prolapse due to chordal elongation or rupture, and resulting in mitral valve regurgitation. Guideline referral for surgical intervention centres primarily on symptoms and ventricular dysfunction ...
Adams, David H., Falk, Volkmar, Rosenhek, Raphael   +2 more
core  

Perspectives on the revised Ghent criteria for the diagnosis of Marfan syndrome [PDF]

, 2015
Three international nosologies have been proposed for the diagnosis of Marfan syndrome (MFS): the Berlin nosology in 1988; the Ghent nosology in 1996 (Ghent-1); and the revised Ghent nosology in 2010 (Ghent-2).
Bannas, Peter, Behzadi, Cyrus, Bernhardt, Alexander M, Blankenberg, Stefan, De Backer, Julie, Fuisting, Bettina, Hillebrand, Mathias, Kölbel, Tilo, Püschel, Klaus, Robinson, Peter N, Rybczynski, Meike, Schüler, Helke, Sheikhzadeh, Sara, von Kodolitsch, Yskert   +13 more
core   +2 more sources

Long‐Term Impact of Prosthesis‐Patient Mismatch After Transcatheter Aortic Valve Replacement in Patients With Small Aortic Annuli

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Prosthesis‐patient mismatch (PPM) remains common following transcatheter aortic valve replacement (TAVR) and is associated with worse clinical outcomes. PPM is of particular concern in small aortic annuli (SAA). Aims To compare the incidence, predictors, and long‐term impact of PPM in SAA TAVR.
Itamar Loewenstein, Bar Gitter, Tamar Itach, Yaron Arbel, Jeremy Ben‐Shoshan, Maayan Konigstein, Ariel Finkelstein, Amir Halkin, Shmuel Banai, Arie Steinvil   +9 more
wiley   +1 more source

Best treatment option for secondary mitral regurgitation surgery: a network meta-analysis of randomized and non-randomized controlled studies

Scientific Reports
The objective of this study is to ascertain whether subvalvular papillary muscle repair in conjunction with restrictive mitral valve annuloplasty represents the most efficacious treatment for patients presenting with secondary ischemic mitral ...
Francesco Nappi, Antonio Salsano, Arnaldo Dimagli, Francesco Santini, IvanCarmine Gambardella, Omar Ellouze   +5 more
doaj   +1 more source

Repair Versus Replacement in Mitral Valve Endocarditis Due to Methicillin-Susceptible Staphylococcus aureus

Pathogens
Background: The guidelines recommend mitral valve repair whenever possible in patients undergoing surgical treatment for active infective endocarditis of the native mitral valve.
Zaki Haidari, Iskandar Turaev, Stephan Knipp, Mohamed El-Gabry   +3 more
doaj   +1 more source

Hammock mitral valve: A rare case report

Journal of the Scientific Society, 2014
Congenital mitral stenosis is a relatively rare disorder comprising 0.2% of all congenital heart defects. Hammock mitral valve producing severe mitral stenosis is a rare variant of congenital mitral stenosis.
Veeresh F. Manvi, M. D. Dixit, Srinivas M. Kini, Nidhi Goel Manvi, Anand Vagrali, Sharan Patil   +5 more
doaj   +1 more source

Use of a sandwich technique to repair a left ventricular rupture after mitral valve replacement [PDF]

, 2014
One difficulty with external repair of left ventricular rupture after mitral valve replacement is collateral bleeding in friable myocardium adjacent to the rupture.
Lee, Anthony W, Lee, Myles E, Tamboli, Mallika   +2 more
core   +2 more sources

Comprehensive Nursing Management of Anticoagulation and Heart Failure Surveillance in a Chinese Patient With Mirror‐Image Dextrocardia Post‐MitraClip Surgery: A First Case Report

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Mitral regurgitation (MR) is the valent type of valvular heart disease, caused by primary leaflet lesions or annular dilatation secondary to left ventricular dysfunction. It can lead to a series of complications such as volume overload, exacerbated pulmonary congestion, and heart failure, significantly impacting patient prognosis ...
Juelian Li, Chun Wu, Chao Shang, Yu Deng, Jinxia Zhang   +4 more
wiley   +1 more source

Longitudinal Outcomes Following Mitral Valve Repair for Infective Endocarditis

Microorganisms
Mitral valve repair is the ideal approach in managing mitral valve infective endocarditis for patients requiring surgery. However, viable repair is influenced by the extent of valve destruction and there can be technical challenges in reconstruction ...
Yuan Qiu, Lawrence Lau, Zaim Khan, David Messika-Zeitoun, Marc Ruel, Vincent Chan   +5 more
doaj   +1 more source