Results 31 to 40 of about 4,004 (136)

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Successful Percutaneous Retrieval of an Embolized MitraClip From the Right Subclavian Artery

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Single leaflet device attachment (SLDA) after mitral transcatheter valve edge‐to‐edge repair (M‐TEER) has been reported in up to 5% of patients. However, complete embolization of the M‐TEER device is exceedingly rare. Device retrievals in all previously reported cases were completed by vascular surgery cut down at the end. In this case, we are
Seyed Hossein Aalaei‐Andabili, Diljon S. Chahal, Shahab Tour Savadkohi   +2 more
wiley   +1 more source

Double Transeptal Puncture for SAPIEN M3 Transcatheter Mitral Valve Replacement: Initial Experience, Indications, and Technique

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The SAPIEN M3 system has been recently approved for transcatheter mitral valve replacement (TMVR). The transeptal guide sheath is used to deploy the dock, which is completely released before inserting and deploying the M3 valve using the same femoral access, transeptal puncture (TSP) and guide sheath.
Clara Fernandez‐Cordon, David Hoare, Aayush Singal, Sanjeev Bhattacharyya, Suneil K. Aggarwal, Michael J. Mullen   +5 more
wiley   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Sleep‐disordered breathing in valvular heart disease: A Modifiable comorbidity

Sleep Research, EarlyView.
Abstract Sleep‐disordered breathing (SDB) is highly prevalent among patients with valvular heart disease (VHD) and is independently associated with adverse clinical outcomes. The two major phenotypes—obstructive sleep apnea (OSA) and central sleep apnea (CSA)—exhibit distinct distributions across VHD subtypes. CSA predominates in severe aortic stenosis,
Wu Juan, Chen Ze, Zhang Qun, Chen Qiuyuan, Su Mei, Zhang Xilong, Ding Ning   +6 more
wiley   +1 more source

Dyssynchrony without dysfunction: Left bundle branch block does not acutely reduce cardiac output

The Journal of Physiology, EarlyView.
Abstract figure legend Six electromechanical in silico heart models were simulated under healthy and pure acute left bundle branch block (LBBB) conditions. LBBB induced electrical dyssynchrony and increased left ventricular free wall strain, while the right and left ventricular ejection fraction remained relatively unchanged.
Carola Kruthoff, Jonathan Krauß, Jorge Sánchez, Tobias Gerach, Cristian Barrios Espinosa, Jan‐Erik Duhme, Axel Loewe   +6 more
wiley   +1 more source

MitraClip for Secondary Mitral Regurgitation

JACC: Case Reports, 2021
We describe the case of an 83-year-old man with a history of ischemic cardiomyopathy and severe secondary mitral regurgitation. This case highlights the role of transcatheter edge-to-edge repair with the MitraClip in the management of symptomatic ...
Brian D. McCauley, MD, MPH, Howard C. Herrmann, MD, Tiffany Chen, MD, Saif Anwaruddin, MD   +3 more
doaj   +1 more source

The durability of different anchoring points and anchoring types in the left ventricle in an ex vivo porcine model

Clinical Physiology and Functional Imaging, Volume 46, Issue 6, November 2026.
Abstract Objective Surgical mitral valve repair, including anchoring in different parts of the mitral apparatus, is the standard of care for severe mitral regurgitation. Various percutaneous approaches have been developed and are currently under development, but are struggling with durable results.
Henrik Bjursten, Per Wierup, Sasha Koul, Matthias Götberg, Magnus Dencker   +4 more
wiley   +1 more source

Emerging Transcatheter Therapies for Valvular Heart Disease: Focus on Mitral and Tricuspid Valve Procedures

Life
The emergence of percutaneous treatment options provides novel therapeutic alternatives for older and feeble patients who are at high risk for any surgical procedure.
Nikolaos Ktenopoulos, Odysseas Katsaros, Anastasios Apostolos, Maria Drakopoulou, Grigorios Tsigkas, Constantinos Tsioufis, Periklis Davlouros, Konstantinos Toutouzas, Antonios Karanasos   +8 more
doaj   +1 more source

Interventional Mitral Valve Edge‐to‐Edge Repair in Patients Above 85 Years of Age

Catheterization and Cardiovascular Interventions, Volume 108, Issue 4, Page 1548-1557, October 1, 2026.
ABSTRACT Background Mitral valve transcatheter‐edge‐to‐edge repair (M‐TEER) is routinely performed in patients with severe mitral regurgitation (MR) at high operative risk, frequently including elderly patients. Patients ≥ 85 years, however, are frequently excluded in clinical studies.
Florian Jürgens, Florian Schindhelm, Mohammed Abusharekh, Jürgen Kampf, Matthias Totzeck, Fadi Al‐Rashid, Peter Lüdike, Tienush Rassaf, Amir A. Mahabadi   +8 more
wiley   +1 more source