Results 111 to 120 of about 98,918 (262)

Integrin-mediated mTOR signaling drives TGF-β overactivity and myxomatous mitral valve degeneration in hypomorphic fibrillin-1 mice

The Journal of Clinical Investigation
Mitral valve prolapse is often benign, but progression to mitral regurgitation may require invasive intervention and there is no specific medical therapy.
Fu Gao, Qixin Chen, Makoto Mori, Sufang Li, Giovanni Ferrari, Markus Krane, Rong Fan, George Tellides, Yang Liu, Arnar Geirsson   +9 more
doaj   +1 more source

Transhepatic Access for Mitral Valve Replacement: Transhepatic Transseptal Mitral Valve-in-Valve. [PDF]

JACC Case Rep
Marcondes Lemos LF, Alexandre de Alvim Siqueira D, Augusto Cardoso Pedra C, Cervone AC, Souza MO, Francisco Pinto IM, de Andrade Vilela A, Della Togna DJ, Isabel de Oliveira Ramos A, Feres F.   +9 more
europepmc   +1 more source

Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets

Anaesthesia, EarlyView.
Summary Introduction Uncertainty remains regarding whether the time of day that cardiac surgery is performed affects postoperative outcomes or if the observed variation can be explained by patient or surgical factors. Methods A secondary analysis of prospectively collected data was conducted to examine the association between time of cardiac surgery ...
Gareth Kitchen, Karen Thomas, Tim Felton, Hannah Durrington, John Blaikley, Stuart W. Grant, David Harrison, Peter McGuigan, Kathryn Rowan, Anthony Wilson, Danny McAuley, Paul Dark   +11 more
wiley   +1 more source

Hemocompatibility Outcomes After Aspirin Withdrawal in Long‐Term HeartMate 3 Left Ventricular Assist Device Patients on Vitamin K Antagonists

Artificial Organs, EarlyView.
Aspirin discontinuation in long‐term, stable Heart Mate 3 LVAD patients maintained on Vitamin K antagonists did not increase hemocompatibility‐related adverse events. These findings support the safety of simplified antithrombotic therapy and extend randomized evidence for aspirin avoidance to the long‐term management of Heart Mate 3 recipients ...
Melanie Arnreiter, Barbara Karner, Hebe Al Asadi, Christina Abd El‐Malak, Christiane Marko, Daniel Zimpfer, Julia Riebandt, Roxana Moayedifar, Thomas Schlöglhofer   +8 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

Mechanisms of mitral valve development and disease. [PDF]

Front Cardiovasc Med
Wang E, Zhou B.
europepmc   +1 more source

Three Ventricular Assist Devices (True TriVAD) as Bridge to Durable Biventricular Support (BiVAD) in LVAD Patient With Severe Aortic Regurgitation

Artificial Organs, EarlyView.
An LVAD patient with severe aortic regurgitation (AR) developed right heart failure and multi‐organ dysfunction (MOD). tRVAD support caused LV overload and pulmonary edema. Impella 5.5 implantation successfully unloaded the LV and stabilized the patient, enabling durable RVAD implantation with surgical aortic valve replacement.
Nikolaos Cholevas, Felix Schoenrath, Nicolas Merke, Denis Fries, Marcus Mueller, Johanna Mulzer, Evgenij Potapov   +6 more
wiley   +1 more source

Outcomes of mitral valve repair in dogs with myxomatous mitral valve disease and preoperative atrial fibrillation. [PDF]

J Vet Intern Med
Kurogochi K, Endo A, Nishiyama M, Uechi M.   +3 more
europepmc   +1 more source

Outcomes in Patients Requiring VENO‐Venous Extracorporeal Membrane Oxygenation After Cardiac Surgery: An Analysis From the PELS‐1 Study

Artificial Organs, EarlyView.
We report an insight from the PELS‐1– a multicentre, international registry focusing on postocardiotomy extracorporeal support use between 2000 and 2020. We focused on 24/2163 (1.1%) patients requiring V‐V ECMO after cardiac surgery. Mortality was high, with 21.7% of patients discharged alive and an overall 1‐year survival probability of 12.5 ...
Pasquale Nardelli, Silvia Mariani, Maria Elena De Piero, Bas C. T. van Bussel, Michele Di Mauro, Ann‐Kristin Schaefer, Diyar Saeed, Matteo Pozzi, Luca Botta, Udo Boeken, Robertas Samalavicius, Karl Bounader, Xiaotong Hou, Jeroen J. H. Bunge, Hergen Buscher, Leonardo Salazar, Bart Meyns, Michael A. Mazzeffi, Marco L. Sacha Matteucci, Sandro Sponga, Kollengode Ramanathan, Claudio Russo, Francesco Formica, Pranya Sakiyalak, Antonio Fiore, Daniele Camboni, Giuseppe Maria Raffa, Rodrigo Diaz, I‐wen Wang, Jae‐Seung Jung, Jan Belohlavek, Vin Pellegrino, Giacomo Bianchi, Matteo Pettinari, Alessandro Barbone, José P. Garcia, Kiran Shekar, Glenn Whitman, Roberto Lorusso, PELS Investigators   +39 more
wiley   +1 more source

Cryoablation and radiofrequency ablation during mitral valve surgery for rheumatic mitral valve disease: a retrospective cohort study. [PDF]

Front Cardiovasc Med
Nurbay Z, Dzhumabekov A, Kuanishbekova R, Tuleutayev R, Musrepov N.   +4 more
europepmc   +1 more source