Results 181 to 190 of about 744,244 (413)

Trametinib alters contractility of paediatric Noonan syndrome‐associated hypertrophic myocardial tissue slices

open access: yesESC Heart Failure, EarlyView.
Abstract Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP) kinase (MAPK) pathway in severely affected RAS‐CM patients.
Jules Hamers   +11 more
wiley   +1 more source

Mitral valve repair in Barlow disease

open access: yesПатология кровообращения и кардиохирургия, 2015
A mitral valve prolapse nowadays is the most common cause of mitral insufficiency in the western countries and is associated with high morbidity and mortality.
В. М. Назаров   +2 more
doaj   +1 more source

The Electrocardiographic Pattern of Right Ventricular Hypertrophy in Mitral Valve Disease [PDF]

open access: bronze, 1955
Ralph C. Scott   +3 more
openalex   +1 more source

Transcoronary study of biomarkers in patients with heart failure: Insights into intracardiac production

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Biomarkers are pivotal in the management of heart failure (HF); however, their lack of cardiac specificity could limit clinical utility. This study aimed to investigate the transcoronary changes and intracardiac production of these biomarkers.
Jie Ren   +10 more
wiley   +1 more source

Percutaneous transfemoral-transseptal implantation of a second-generation CardiAQ mitral valve bioprosthesis: first procedure description and 30-day follow-up.

open access: yesEuroIntervention, 2016
AIMS Transcatheter mitral valve implantation for mitral valve regurgitation is in the very early phase of development because of challenging anatomy and device dimensions. We describe the procedure of a transfemoral-transseptal implantation of the second-
G. Ussia   +8 more
semanticscholar   +1 more source

Mitral valve transcatheter edge‐to‐edge repair in the elderly—A safe and effective therapy

open access: yesESC Heart Failure, EarlyView.
Mitral valve transcatheter edge‐to‐edge repair in elderly patients is safe and offers comparable mitral valve regurgitation reduction and symptom relief to younger patients. At 3 years, increased all‐cause mortality is observed in elderly patients with advanced heart failure and elevated EuroSCORE II.
Dominik Felbel   +6 more
wiley   +1 more source

Predicting Mitral Valve mTEER Surgery Outcomes Using Machine Learning and Deep Learning Techniques [PDF]

open access: yesarXiv
Mitral Transcatheter Edge-to-Edge Repair (mTEER) is a medical procedure utilized for the treatment of mitral valve disorders. However, predicting the outcome of the procedure poses a significant challenge. This paper makes the first attempt to harness classical machine learning (ML) and deep learning (DL) techniques for predicting mitral valve mTEER ...
arxiv  

A coupled mitral valve -- left ventricle model with fluid-structure interaction [PDF]

open access: yesarXiv, 2017
Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now possible to explore the mechanics of valve-heart interactions using anatomically and physiologically realistic ...
arxiv  

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