Results 221 to 230 of about 137,000 (312)

Acquired Gerbode Defect Diagnosed Seven Years After Surgical Mitral Valve Repair for Severe Primary Mitral Valve Regurgitation: A Case Report. [PDF]

Cureus
Kazma H, Iskandar S, Hitti J, Rachid A, Mohammed M.   +4 more
europepmc   +1 more source

Selective RyR2 inhibition reduces arrhythmia susceptibility in human cardiac slices

The Journal of Physiology, EarlyView.
Abstract figure legend ent‐Vert selectively inhibits RyR2‐mediated sarcoplasmic reticulum (SR) Ca2+ leak and prevents triggered activity in human cardiac slices. A, in human ventricular slices exposed to β‐adrenergic stimulation with Iso and RyR2 sensitization with caffeine, RyR2 channels become hyperactive, leading to Ca2+ sarcoplasmic leak and ...
Micah K. Madrid, Katy A. Trampel, Batool Salman, Sharon A. George, Tatiana Efimova, Bjorn Knollmann, Igor R. Efimov   +6 more
wiley   +1 more source

Transcatheter mitral valve replacement in a complex mitral annular calcification anatomy. [PDF]

Eur Heart J Case Rep
Tomai F, De Persio G, Celotto R, Migliaro S, Salatino T.   +4 more
europepmc   +1 more source

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 661-672, March 2026.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim, Alexsandra Christianne Malaquias, Debora Romeo Bertola, Raissa Carneiro Rezende, Laurana De Polli Cellin, Lucas Vieira Lacerda Pires, Ana Maria Santillan‐Vasconez, Antônio Marcondes Lerario, Renata da Cunha Scalco, Alexander Augusto de Lima Jorge   +9 more
wiley   +1 more source

Ultrasonic emulsification to facilitate mitral valve reconstruction in mitral annular calcification. [PDF]

Ann Cardiothorac Surg
Rheault-Henry M, Malik MI, Bhatt N, Gelinas J, Chu MWA.   +4 more
europepmc   +1 more source

A Case of Re-operation for Paravalvular Leakage after Mitral Valve Replacement Complicated by Heparin-Induced Thrombocytopenia

, 2011
Hiroki Kato, Noriyoshi Yashiki, Kenji Iino, Shigeyuki Tomita, Go Watanabe   +4 more
openalex   +2 more sources

Evaluating the Genetic Overlap Between Congenital Heart Disease and Neuroblastoma Risk

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Children with congenital heart disease (CHD) have elevated neuroblastoma (NB) risk, potentially due to shared neural crest origins. We analyzed rare exonic de novo single‐nucleotide variants in 702 CHD and 454 NB trios from the Neuroblastoma Epidemiology in North America Study, Gabriella Miller Kids First Program, and a published cohort. Seven
Ji Yun Tark, Alexander Renwick, Yao Yu, Aniko Sabo, Andrew F. Olshan, Sharon E. Plon, Chad D. Huff, Philip J. Lupo   +7 more
wiley   +1 more source

Three-dimensional assessment of the mitral valve in clinical practice. [PDF]

Eur Heart J Imaging Methods Pract
Viva T, Fiore C, Lancellotti P.
europepmc   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

The Anatomical Record, Volume 309, Issue 2, Page 417-450, February 2026.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Tasha K. Phillips, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar   +16 more
wiley   +1 more source

Tips and tricks in addressing mitral annular calcification in mitral valve surgery. [PDF]

Ann Cardiothorac Surg
Elbatarny M, David TE.
europepmc   +1 more source