Results 111 to 120 of about 113,171 (303)

Prognostic value of NT‐proBNP in patients with primary mitral regurgitation undergoing transcatheter edge‐to‐edge repair

European Journal of Heart Failure, Volume 27, Issue 12, Page 2921-2934, December 2025.
In the PRIME‐MR study, patients with higher N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) tertiles more frequently reached death or heart failure hospitalization (HFH) within 3 years. Log‐transformed NT‐proBNP levels independently predicted the primary endpoint (adjusted hazard ratio 1.17, 95% confidence interval 1.07–1.28; p < 0.001).
Philipp von Stein, Jessica Weimann, Roman Pfister, Sebastian Ludwig, Benedikt Koell, Erwan Donal, Dhairya Patel, Lukas Stolz, Tetsu Tanaka, Andrea Scotti, Teresa Trenkwalder, Felix Rudolph, Daryoush Samim, Cristina Giannini, Julien Dreyfus, Jean‐Michel Paradis, Marianna Adamo, Nicole Karam, Yohann Bohbot, Anne Bernard, Bruno Melica, Angelo Quagliana, Yoan Lavie Badie, Mirjam Kessler, Omar Chehab, Simon Redwood, Edith Lubos, Lars Sondergaard, Marco Metra, Chiara Primerano, Fabien Praz, Muhammed Gerçek, Erion Xhepa, Georg Nickenig, Azeem Latib, Niklas Schofer, Raj Makkar, Juan F. Granada, Thomas Modine, Jörg Hausleiter, Augustin Coisne, Daniel Kalbacher, Christos Iliadis, on behalf of the PRIME‐MR Investigators, Paul Achouh, David Attias, Stephan Baldus, Alain Berrebi, Guillaume Bonnet, Laura Granada, Frederic Bouisset, Corentin Bourg, Thierry Bourguignon, Diogo Ferreira, Stéphane Lafitte, Thibault Lhermusier, Guillaume L'official, Mohammed Nejjari, Edoardo Pancaldi, Lydia X. Plewe, Tobias Rheude, Natacha Rousse, Volker Rudolph, Dan Rusinaru, Christophe Saint‐Etienne, Francisco Sampaio, Jury Schewel, Arnaud Sudre, Christophe Tribouilloy, Marcel Weber, Stephan Windecker   +70 more
wiley   +1 more source

Mitral regurgitation in patients with severe aortic stenosis: Diagnosis and management [PDF]

, 2018
Severe aortic stenosis (AS) and mitral regurgitation (MR) frequently coexist. Although some observational studies have reported that moderate or severe MR is associated with higher mortality, the optimal management of such patients is still unclear ...
Grayburn, P. A., Sannino, A.
core   +1 more source

Role of Angiotensin Receptor Blockers on Cardiovascular Protection in Marfan Syndrome: A Literature Review

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Marfan Syndrome (MFS) is a hereditary connective tissue disorder with severe cardiovascular complications, including aortic aneurysms and dissections. Current therapies, such as beta‐blockers, have limitations in preventing disease progression.
Hashim Mohamed Siraj, Sakshi P. Bidkar, Muhammad Hassan, Nivedita Pant, Muhammad Husnain Ahmad, Masab Ali, Onyekachi Emmanuel Anyagwa, Zuha Zafar, Sumbla Fayyaz, Muhammad Irfan   +9 more
wiley   +1 more source

Clinical significance of cardiac murmurs: get the sound and rhythm! [PDF]

, 2014
C
van Loon, Gunther
core   +1 more source

Familial occurrence of mitral regurgitation in patients with mitral valve prolapse undergoing mitral valve surgery

European Journal of Preventive Cardiology, 2019
Background Initial studies have suggested the familial clustering of mitral valve prolapse, but most of them were either community based among unselected individuals or applied non-specific diagnostic criteria.
Y. Hiemstra, A. V. van Wijngaarden, M. Bos, M. Schalij, R. Klautz, Jeroen J. Bax, V. Delgado, D. Barge-Schaapveld, N. Marsan   +8 more
semanticscholar   +1 more source

Integrin-mediated mTOR signaling drives TGF-β overactivity and myxomatous mitral valve degeneration in hypomorphic fibrillin-1 mice

The Journal of Clinical Investigation
Mitral valve prolapse is often benign, but progression to mitral regurgitation may require invasive intervention and there is no specific medical therapy.
Fu Gao, Qixin Chen, Makoto Mori, Sufang Li, Giovanni Ferrari, Markus Krane, Rong Fan, George Tellides, Yang Liu, Arnar Geirsson   +9 more
doaj   +1 more source

A Lumped Parameter Model to Study Atrioventricular Valve Regurgitation in Stage 1 and Changes Across Stage 2 Surgery in Single Ventricle Patients [PDF]

, 2018
Goal: This manuscript evaluates atrioventricular valve regurgitation (AVVR) in babies born with an already very challenging heart condition, i.e. with single ventricle physiology.
Baker, Catriona, Corsini, Chiara, Hsia, Tain-Yen, Pant, Sanjay, Pennati, Giancarlo, Vignon-Clementel, Irene   +5 more
core   +2 more sources

Challenges in rheumatic valvular disease: Surgical strategies for mitral valve preservation [PDF]

, 2015
In developing countries, rheumatic fever and carditis still constitutes a major public health problem. Patients have special characteristics that differ from those with rheumatic mitral valve disease we still see in developed countries.
Antunes, MJ
core   +1 more source

Morphofunctional Abnormalities of Mitral Annulus and Arrhythmic Mitral Valve Prolapse

Circulation Cardiovascular Imaging, 2016
Background—Arrhythmic mitral valve prolapse (MVP) is characterized by myxomatous leaflets and left ventricular (LV) fibrosis of papillary muscles and inferobasal wall.
M. Perazzolo Marra, C. Basso, M. De Lazzari, S. Rizzo, A. Cipriani, Benedetta Giorgi, C. Lacognata, I. Rigato, F. Migliore, K. Pilichou, L. Cacciavillani, E. Bertaglia, A. Frigo, B. Bauce, D. Corrado, G. Thiene, S. Iliceto   +16 more
semanticscholar   +1 more source

Mitral valve prolapse: clinical variants, current understanding

Лечащий Врач, 2021
The article covers clinical diversity of mitral prolapse, deliberating ambiguous prognosis in patients with mitral valve prolapse (MVP) and different tactics of their management. The greatest attention is paid to primary MVP as the only variant of mitral
A. V. Klemenov
doaj