Results 141 to 150 of about 75,675 (329)

ZFP36 inhibits the pro‐apoptotic effects of transforming growth factor β1 on mitral valve interstitial cells via the GTP‐binding protein 6 pathway in mitral valve prolapse

open access: yesExperimental Physiology, EarlyView.
Abstract The objective of this work was to investigate the role of ZFP36 in mitral valve prolapse (MVP). Mitral valve and plasma were collected to assess the expression of ZFP36, transforming growth factor β (TGF‐β), collagen and elastin and apoptosis rates.
Meng Zhao   +9 more
wiley   +1 more source

Jefferson Surgeon Performs Minimally Invasive Robotic Mitral Valve Repair [PDF]

open access: yes, 2012
Routine physical exams often reveal the presence of a heart murmur, which can be the first sign of mitral valve prolapse. Typically diagnosed with an echocardiogram, mitral valve prolapse is a condition in which the valve separating the upper and lower ...

core   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark   +3 more
wiley   +1 more source

Paravalvular leakage after mitral valve replacement: improved long-term survival with aggressive surgery? [PDF]

open access: yes, 2017
Background: Following mitral valve replacement, surgical closure of paravalvular leaks is usually advised in severely symptomatic patients and in those requiring blood transfusions for persisting haemolysis.
Franzen, Daniel   +7 more
core  

Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Non‐Newtonian modelling and GPEs for stroke risk in atrial fibrilation patients. Abstract Atrial fibrillation (AF) is the most common heart arrhythmia, linked to a five‐fold increase in stroke risk. The left atrial appendage (LAA), prone to blood stasis, is a common thrombus formation site in AF patients.
Paolo Melidoro   +12 more
wiley   +1 more source

Three-dimensional structure of the flow inside the left ventricle of the human heart

open access: yes, 2013
The laboratory models of the human heart left ventricle developed in the last decades gave a valuable contribution to the comprehension of the role of the fluid dynamics in the cardiac function and to support the interpretation of the data obtained in ...
Cenedese, A.   +3 more
core   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson   +7 more
wiley   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall   +8 more
wiley   +1 more source

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