Results 161 to 170 of about 3,674,243 (341)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

To mix or not to mix—efficient adaptation to windthrow risk

open access: yesEnvironmental Research Communications
Disturbance to spruce forests from wind and bark beetles is projected to worsen. It has been suggested that mixed-species forests could provide a more disturbance-resilient option than spruce monocultures.
Matti Hyyrynen   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Effectiveness and safety of Humalog Mix 50/50 versus Humalog Mix 75/25 in Chinese patients with type 2 diabetes

open access: yesTherapeutics and Clinical Risk Management, 2014
Mohammad Ishraq Zafar,1,* Xinquan Ai,2,* Raja Adeel Shafqat,3 Feng Gao1  1Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 2Zhijiang ...
Zafar MI, Ai X, Shafqat RA, Gao F
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Supplementary material to "Seasonal and interannual variability of the pelagic ecosystem and of the organic carbon budget in the Rhodes Gyre (Eastern Mediterranean): influence of winter mixing"

open access: gold, 2022
Joelle Habib   +10 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Penggunaan Bahan Bakar Alternatif dalam Industri Semen

open access: yesMimbar, 2009
One of the various ways to utilize coal ash from either industrial- or power generation (utility) boilers in form of bottom ash and fly ash is brickmaking.
Stefano Munir
doaj  

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