Results 181 to 190 of about 23,995,861 (305)

Bayesian regularization for a nonstationary Gaussian linear mixed effects model. [PDF]

Stat Med, 2022
Gecili E, Sivaganesan S, Asar O, Clancy JP, Ziady A, Szczesniak RD.   +5 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Evaluating Childhood Intimate Partner Violence and Adolescent Bullying and Cyberbullying Perpetration: A Longitudinal 2-Part Mixed-Effects Model Approach. [PDF]

J Prim Care Community Health
Feng S, Li C, Yu F, Kwok OM, Lawrence T.
europepmc   +1 more source

A Mixed-Effects Model of Associations Between Interleukin-6 and Hippocampal Volume. [PDF]

J Gerontol A Biol Sci Med Sci, 2022
Harrell ER, Bui C, Newman SD, Alzheimer’s Disease Neuroimaging Initiative (ADNI).   +3 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The Impact of Anosmia on Intimacy: A Linear Mixed-Effects Model Analysis of Sexual Wellbeing Following COVID-19. [PDF]

Int J Environ Res Public Health
Miclet A, Mollaioli D, Lauriola M, Ciocca G, Sansone A, Jannini EA, Limoncin E.   +6 more
europepmc   +1 more source

Modeling dragonfly population data with a Bayesian bivariate geometric mixed-effects model. [PDF]

J Appl Stat, 2023
van Oppen YB, Milder-Mulderij G, Brochard C, Wiggers R, de Vries S, Krijnen WP, Grzegorczyk MA.   +6 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Preoperative Functional Disability and Perioperative Life-space Mobility in Older Patients with Lumbar Spinal Stenosis: A Generalized Linear Mixed-effects Model Analysis. [PDF]

Phys Ther Res
Ishizuka D, Nozaki S, Minezaki H, Ota T, Asakawa Y.   +4 more
europepmc   +1 more source

An ensemble mixed effects model of sleep loss and performance. [PDF]

J Theor Biol, 2021
Cochrane C, Ba D, Klerman EB, St Hilaire MA.   +3 more
europepmc   +1 more source