Results 61 to 70 of about 23,995,861 (305)
Behaviour of the additive finite locus model [PDF]
, 1999 A finite locus model to estimate additive variance and the breeding values was implemented using Gibbs sampling. Four different distributions for the size of the gene effects across the loci were considered: i) uniform with loci of different effects, ii)
Ricardo Pong-Wong +7 more
core +1 more source
Corruption perceptions and social cohesion in Africa: the role of institutional quality
Cogent Social SciencesSocial cohesion is vital for societal stability, yet its drivers, particularly in Africa, are not well understood. This paper highlights the role of the public sector in shaping social cohesion, especially through corruption, discrimination, or ...
Frederich Kirsten, Lumengo Bonga-Bonga
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of RespirationBackground: How spontaneously breathing individuals modulate inspiratory pressure and peak inspiratory flow (PIF) during incremental positive end-expiratory pressure (PEEP) loading, and whether this differs across respiratory exposure groups, are ...
Gaetano Gazzè +6 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Coefficients of Determination for Mixed-Effects Models
Journal of Agricultural, Biological and Environmental Statistics, 2022 The coefficient of determination is well defined for linear models and its extension is long wanted for mixed-effects models. We revisit its extension to define measures for proportions of variation explained by the whole model, fixed effects only, and random effects only.
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Conducting Meta-Analyses in R with the metafor Package
Journal of Statistical Software, 2010 The metafor package provides functions for conducting meta-analyses in R. The package includes functions for fitting the meta-analytic fixed- and random-effects models and allows for the inclusion of moderators variables (study-level covariates) in these
Wolfgang Viechtbauer
doaj
Multivariate Dose-Response Meta-Analysis: The dosresmeta R Package
Journal of Statistical Software, 2016 An increasing number of quantitative reviews of epidemiological data includes a doseresponse analysis. Aims of this paper are to describe the main aspects of the methodology and to illustrate the novel R package dosresmeta developed for multivariate dose-
Alessio Crippa, Nicola Orsini
doaj +1 more source