Results 151 to 160 of about 6,353,635 (345)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
MIXED-MODE Ⅰ-Ⅱ FRACTURE BEHAVIOR OF FV520B STEEL
Jixie qiangdu, 2019 A mixed-mode I-II fracture fixture and modified compact tensile specimen are designed to investigate mixed-mode I-II fracture behavior of FV520 B stainless steel used in centrifugal compressor impeller.
WEI RenChao +6 more
doaj
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Mode effect or question wording? Measurement error in mixed mode surveys. [PDF]
[Dataset available: http://hdl.handle.net/10411/17672]
Hox, J.J.C.M. +2 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
, 2011 A mixed-mode method for operating a vehicle's propulsion plant to travel at a selected average speed using the minimum amount of fuel. The method involves travelling in one mode at high speed part of the time, and in a different mode at low speed part of the time, in such a way that the average speed is the selected value.
Brown, Gerald Gerard +4 more
openaire +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
, 2006 However, the availability in the 1950s of large-scale mechanical cooling, along with other technologies such as curtain walls and fluorescent lighting, led to the more common building forms we see today in North America—typically all-glass, flush-skin buildings with large floor plates and no operable windows.Our technological capabilities allow ...
openaire +1 more source
Double noding technique for mixed mode crack propagation studies [PDF]
A simple dynamic finite element algorithm for analyzing a propagating mixed mode crack tip is presented. A double noding technique, which can be easily incorporated into existing dynamic finite element codes, is used together with a corrected J integral ...
Emergy, A. F. +2 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source