Results 31 to 40 of about 232,906 (263)

Multiplicity within Singularity: Racial Categorization and Recognizing “Mixed Race” in Singapore

open access: yesJournal of Current Southeast Asian Affairs, 2011
“Race” and racial categories play a significant role in everyday life and state organization in Singapore. While multiplicity and diversity are important characteristics of Singaporean society, Singapore's multiracial ideology is firmly based on separate,
Zarine L. Rocha
doaj   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Comparison of serum creatinine levels in different color/race categories in a Brazilian population

open access: yesCadernos de Saúde Pública, 2015
Serum creatinine (sCr) is usually higher among black people in the United States due to increased muscle mass, justifying the addition of race adjustment in creatinine-based formulas to estimate glomerular filtration rate (eGFR).
Roberto Carlos de Brito Barcellos   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mixed race thought: making and unmaking (mixed) race

open access: yesCritique of Anthropology
Across the globe, racial and ethnic categories continue to play a central role in the regulation and organisation of social and political life. Mixed-race in all its forms requires us to move beyond categorical thinking and question epistemological and methodological singularities.
openaire   +3 more sources

New Routes to Mixed “Roots”

open access: yesGenealogy, 2022
Developments in reproductive (e.g., assisted reproduction, surrogacy) and genetic technologies (commercial DNA ancestry testing) have opened new routes to mixedness that disrupt the relationship between multiracialism and family.
Kimberly DaCosta
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Multiracial Identities in the United States: Towards the Brazilian or South African Paths?

open access: yesSocial Sciences, 2022
Multiracial identities in Brazil, South Africa, and the United States all formed within White supremacist, White racist, and anti-Black social orders.
G. Reginald Daniel
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Correlation trends for bone mineral density in Mexican women: evidence of familiar predisposition Tendencias de correlación para la densidad mineral ósea en mujeres mexicanas: pruebas de predisposición familiar

open access: yesSalud Pública de México, 2009
OBJECTIVE: Genetic factors determine bone mineral density (BMD) and peak bone density between 20 and 30 years of age, as well as bone mineral loss after menopause.
Eduardo Lazcano-Ponce   +4 more
doaj  

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