Results 61 to 70 of about 278,285 (307)

Mixed-race thought – making and unmaking (mixed) race

open access: yesCritique of Anthropology
Across the globe, racial and ethnic categories continue to play a central role in the regulation and organisation of social and political life. Mixed-race in all its forms requires us to move beyond categorical thinking and question epistemological and methodological singularities.
openaire   +2 more sources

Excursus on Hapa; or the Fate of Identity [PDF]

open access: yes, 2012
This paper focuses on the contradictions and tensions inherent in self-identification and oppositional identities. In the past twenty years, Hapa has emerged as an oppositional identity used by mixed-race Asian Americans.
Rabin, Nicole Myoshi
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Why I Write So Many Books About Race

open access: yesJournal of World Philosophies, 2016
I relate how my life has intersected with my work in philosophy, both before and after a twenty-year absence from academia. Motivations for engaging in Philosophy of Race may be different from other projects because the subject itself is urgent and the ...
Naomi Zack
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Beyond ‘race’?: a rejoinder

open access: yesComparative Migration Studies, 2023
In this rejoinder we argue, based on the papers of this commentary series, that ‘race’ is such a tricky notion because it can be used in (at least) two very different and contradictory ways—as a concept to disentangle racism and racialisation (what M ...
Tabea Scharrer, Sawitri Saharso
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

The Plight of Mixed Race Adolescents [PDF]

open access: yes
Over the past 40 years, the fraction of mixed race black-white births has increased nearly nine-fold. There is very little empirical evidence on how these children fare relative to their single-race counterparts.
Fryer, Roland G.   +3 more
core   +1 more source

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