Results 111 to 120 of about 982,511 (289)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Economies of Scope in Endangered-Species Protection: Evidence from Interest-Group Behavior [PDF]

This paper looks for positive spillovers from the legal protection of one species to the welfare of others, and for evidence of economies of scope in the costs associated with protecting species under the Endangered Species Act.
Ando, Amy
core  

Mixed-model Analyses for the Primary and Secondary Outcomes: Rates of Changes over Time within Both Groups. [PDF]

, 2017
Mixed-model Analyses for the Primary and Secondary Outcomes: Rates of Changes over Time within Both Groups.
Bea Hemmen (3633202), Peter R. G. Brink (3633211), Ton Ambergen (295464), Ans I. E. Bouman (3633208), Pieter E. Vos (3633205), Henk van de Meent (731131), Henk A. M. Seelen (563131), Silvia M. A. A. Evers (643477)   +7 more
core   +1 more source

Phenotypic Variation of the Invasive Plant Ageratum conyzoides and Analysis of Its Competitiveness With the Co‐Occurring Indigenous Species Perilla frutescens

Ecology and Evolution
Ageratum conyzoides is a malignant invasive plant in China. In this study, we sought to clarify the phenotypic variation of this plant and its competitive interaction with the indigenous species Perilla frutescens .
Xubo Chen, Yafen Zhang, Jianchun Chen, Zhengrong Luo, Yuqin Tan, Mengting Yu, Yiran Wu, Chengyu Zhou, Zhixin Xu   +8 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimizing Entomofauna Sampling: A Multi-Stimulus Trap for Sustainable Pest Management in Agroforestry

EntomoBrasilis
Monitoring insect diversity is crucial for understanding ecosystem dynamics and supporting sustainable agricultural practices. Efficient trapping methods are essential tools for assessing entomofauna in complex agroforestry systems.
Adriano Tomaz, Matheus Rodrigues do Nascimento, Francisco Sérgio Neres da Silva, Katiuchia Pereira Takeuchi, Gerson Adriano Silva   +4 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Tree species preferences for foraging site and ways in which the preferences affect the distribution, abundance and species composition of arboreal woodland avifauna [PDF]

, 1989
The tree species preferences by six arboreal bird species and their role in structuring the bird communities in woodland were investigated in two sites in County Durham.
Peck, Kirsi Marianne
core