Results 231 to 240 of about 4,572,954 (287)

Vancomycin Overdose and Infusion Rate Error Leading to a Mixed Anticholinergic-Type Syndrome in a Hemodialysis Patient: A Case Report. [PDF]

J Pharm Technol
Itzayana Guadalupe WR, Francisco Javier AG, Silvia RM, Susanna Edith MG, Juan Manuel MN, Lucila Isabel CP, Del Carmen MR.   +6 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Effectiveness of Interventions for Internet, Smartphone, and Gaming Addictions: Umbrella Review and Meta-Meta-Analysis.

J Med Internet Res
Zhang M, Lan T, Song T, Wang X.
europepmc   +1 more source

Assessing the applicability of big data driven urban vibrancy analysis in mixed urbanized-depopulated contexts: a case study of a Japanese city. [PDF]

Sci Rep
Ishii Y, Hayakawa K.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Spectacular Twisted Mixed-Use Development Resembles Kaleidoscope with Lumiflon

Focus on Powder Coatings, 2019
openaire   +1 more source

Usability and Cultural Relevance of an mHealth App for Hispanic/Latino Individuals Living With Rheumatoid Arthritis: Protocol for a Mixed Methods Study. [PDF]

JMIR Res Protoc
Alves TF, Horner R, Montas MC, Cozad M.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Empowering Quality of Life Monitoring and Self-Management in Bipolar Disorder: Pilot Evaluation of the PolarUs App. [PDF]

Bipolar Disord
Michalak EE, Morton EE, Meyer D, Murray G, O Brien HL, Barnes SJ.   +5 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source