Results 81 to 90 of about 4,572,954 (287)

MIXED USE DEVELOPMENT, KNÍŽECÍ [PDF]

open access: yes
Tématem diplomové práce je doplnění městského bloku na Smíchově v Praze. S ohledem na danou lokalitu v blízkosti brownfieldu Smíchovského nádraží a její budoucí vývoj je nově navrhovaná stavba koncipována jako solid.
Bočan Petr
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Re-Imagining High-Density Mixed-Use Streets

open access: yesProceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA
This paper analyses the essential role of mixed-use streets in contemporary cities and addresses their inherent issues. The study highlights the national policy focus on mixed-use streets, which can improve sustainability, economic development, social ...
Somi Sareen, Mazharul Haque
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

LUD as an Instrument for (Sub)Metropolitanization: The 1000-District in Rishon-Lezion, Israel as a Case Study

open access: yesUrban Planning, 2019
Interest in the role of large urban development (LUD) projects in regeneration efforts of cities has risen in recent years. Studies of their planning process have often focused on global cities, examining challenges associated with their joint (public ...
Eran Weinberg   +2 more
doaj   +1 more source

Encouraging sustainable development in a coastal community: New Hanover County, North Carolina's exceptional design zoning district [PDF]

open access: yes, 2010
While New Hanover County is the second smallest county in North Carolina, it is also the second most densely populated with approximately 850 people per square mile. Nestled between the Cape Fear River and Atlantic Ocean with surrounding barrier island
Ralston, Shawn
core  

Journal Staff [PDF]

open access: yes, 2005
Purpose - This article aims to investigate how R&D employees use their social networks to acquire user information and how this information is used in the development of new products.
Björk, Jennie   +2 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

PENGUKURAN PENGGUNAAN LAHAN CAMPURAN (MIXED USE) DENGAN INDEKS ENTROPY DI KOTA SEMARANG

open access: yesJurnal Riptek, 2019
Mixed use development is one of the supporting aspects of compact city in sustainable urban development that focuses on developing areas with various functions such as residential, commercial, office, and other supporting facilities developed and built ...
Artha Segnita, Wiwandari Handayani
doaj  

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