Results 161 to 170 of about 5,107,925 (306)

Emotional Responses (Intensity/Valence) Fulfill RDoC Criteria but Remain Excluded From Diagnostic Classifications of Mood Disorders. [PDF]

Bipolar Disord
Henry C, Müh C, de Badts CH, Alonso M, Berkovitch L.   +4 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Mixed oligopoly, vertical product differentiation and fixed quality-dependent costs [PDF]

A private and a public firm face fixed quality-dependent costs of production and compete first in quality and then either in prices or in quantities. In the long run the public firm targets welfare maximization whereas the private firm maximizes profits.
Mario Pezzino, Stefan Lutz
core  

Frequency of Human Brucellosis Complications in West Asia: A Systematic Review and Meta-Analysis. [PDF]

Microbiologyopen
Fakhri-Demeshghieh A, Rostamzaman E, Sayareh F, Nikoukar A, Farahani F, Bakhtiary Nia F, Sepahvand H, Khaleghi M, Azamian M, Shirzadi MR, Akbarein H, Rahmanian V.   +11 more
europepmc   +1 more source

Mixed-mechanism analgesics for mixed pain

Frontiers in Medicine
The concept of “mixed pain” simultaneously highlights the benefit of integration of emerging advances in basic science (in particular, physiologic mechanisms) with advances in clinical care (symptomatology and diagnosis), and highlights some current prevailing challenges for both.
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Mixed strategies in baseball, dating and paying your taxes [Game theory]

, 2014
Educação Superior::Ciências Exatas e da Terra::Ciência da ComputaçãoPresents a class about game theory. In this lecture is presented three different interpretations of mixed strategies in various contexts: sport, anti-terrorism strategy, dating, paying ...
Polak, Ben
core  

Comparative Immunohistochemical Study of Canine Mammary Tumours: Introducing of Triple-Negative Profile (ER^-/PR^-/HER2^-) in Benign Mammary Tumours of Animal Model. [PDF]

Vet Med Sci
Lak H, Amniattalab A.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Portraying Mixed-Agenda Couples: Insights From Large-Scale Data Sets. [PDF]

J Marital Fam Ther
Tang Y, Anderson SR, Johnson LN, Harris SM, Kateregga A.   +4 more
europepmc   +1 more source