Results 241 to 250 of about 5,107,925 (306)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Penalized Cumulative Probability Model for a Continuous Outcome Subject to Detection Limits. [PDF]

Stat Med
Sun S, Mas VR, Archer KJ.
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Evaluating the internal architecture of the postnatal human maxilla across the stages of tooth development and eruption. [PDF]

Surg Radiol Anat
Mhlathi X, Small C, Hutchinson EF.
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Artificial gene clusters designed for simultaneous multi-gene expression enable reconstruction of metabolite biosynthesis pathways in <i>Trichoderma reesei</i>. [PDF]

Synth Syst Biotechnol
Wang L, Dang Y, Luan C, Yan Z, Wang X, Ma Z, Zhang X, Ao R, Liu B, Liu Z, Shi P, Xie J.   +11 more
europepmc   +1 more source

Correction: Cost of illness of scrub typhus in South India - a population-based, mixed-methods study. [PDF]

PLoS Negl Trop Dis
Devamani C, Biran A, Ariyoshi K, John KR, Ross I, Kubo Y, Chandramohan D, Prabhakar Abhilash KP, Schmidt WP.   +8 more
europepmc   +1 more source

Visual sources and information usefulness in the second-hand market: User-generated, firm-generated, and mixed photos across price conditions. [PDF]

PLoS One
Cao X, Yaacob A, Chong KM.
europepmc   +1 more source