Results 121 to 130 of about 691,938 (340)

Mixed finite difference method for singularly perturbed differential difference equations with mixed shifts via domain decomposition

Ain Shams Engineering Journal, 2018
In this paper, a mixed finite difference method is proposed to solve singularly perturbed differential difference equations with mixed shifts, solutions of which exhibit boundary layer behaviour at the left end of the interval using domain decomposition.
Lakshmi Sirisha, K. Phaneendra, Y.N. Reddy   +2 more
doaj   +1 more source

Global existence of weak solutions for strongly damped wave equations with nonlinear boundary conditions and balanced potentials

, 2018
We demonstrate the global existence of weak solutions to a class of semilinear strongly damped wave equations possessing nonlinear hyperbolic dynamic boundary conditions.
Shomberg, Joseph L.
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Mixed Convection in a Square Cavity Filled with Porous Medium with Bottom Wall Periodic Boundary Condition

, 2023
Ihsan Y. Hussein, Luma F. Ali
openalex   +2 more sources

Quasilinear parabolic systems with mixed boundary conditions

, 2006
In this paper we investigate quasilinear systems of reaction-diffusion equations with mixed Dirichlet-Neumann bondary conditions on non smooth domains. Using techniques from maximal regularity and heat-kernel estimates we prove existence of a unique solution to systems of this type.
Hieber, Matthias, Rehberg, Joachim
openaire   +2 more sources

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Non-steady magneto-hydrodynamics-heat system with joule and buoyancy effects under mixed boundary conditions

Electronic Journal of Differential Equations
This article concerns the non-steady magneto-hydro-dynamics (MHD) heat system with Joule and buoyancy effects under mixed boundary conditions. The boundary conditions for fluids can include the stick, total pressure, vorticity, total stress conditions ...
Tujin Kim
doaj  

A full potential inverse method based on a density linearization scheme for wing design [PDF]

A mixed analysis inverse procedure based on the full potential equation in conservation form was developed to recontour a given base wing to produce density linearization scheme in applying the pressure boundary condition in terms of the velocity ...
Shankar, V.
core   +1 more source