Results 51 to 60 of about 691,938 (340)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

On the Local Well-posedness of a 3D Model for Incompressible Navier-Stokes Equations with Partial Viscosity [PDF]

open access: yes, 2011
In this short note, we study the local well-posedness of a 3D model for incompressible Navier-Stokes equations with partial viscosity. This model was originally proposed by Hou-Lei in \cite{HouLei09a}.
Hou, Thomas Y., Shi, Zuoqiang, Wang, Shu
core   +1 more source

Galerkin Methods for Boltzmann-Poisson transport with reflection conditions on rough boundaries

open access: yes, 2018
We consider in this paper the mathematical and numerical modelling of reflective boundary conditions (BC) associated to Boltzmann - Poisson systems, including diffusive reflection in addition to specularity, in the context of electron transport in ...
Escalante, Jose A. Morales   +1 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Unsteady 3D-Navier-Stokes System with Tresca's Friction Law

open access: yes, 2015
Motivated by extrusion problems, we consider a non-stationary incompress-ible 3D fluid flow with a non-constant (temperature dependent) viscosity, subjected to mixed boundary conditions with a given time dependent velocity on a part of the boundary and ...
Boukrouche, Mahdi   +2 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Interdecadal variability and oceanic thermohaline adjustment [PDF]

open access: yes, 1996
Changes in the strength of the thermohaline overturning circulation are associated, by geostrophy, with changes in the east-west pressure difference across an ocean basin.
Bryan   +35 more
core   +1 more source

Mixed boundary conditions as limits of dissipative boundary conditions in dynamic perfect plasticity

open access: yes, 2022
This paper addresses the well posedness of a dynamical model of perfect plasticity with mixed boundary conditions for general closed and convex elasticity sets. The proof relies on an asymptotic analysis of the solution of a perfect plasticity model with relaxed dissipative boundary conditions obtained in [7].
Babadjian, Jean-Francois, Llerena, Randy
openaire   +3 more sources

Subcritical nonlocal problems with mixed boundary conditions

open access: yesBulletin of Mathematical Sciences, 2023
By using linking and [Formula: see text]-theorems in this paper we prove the existence of multiple solutions for the following nonlocal problem with mixed Dirichlet–Neumann boundary data, [Formula: see text] where [Formula: see text], [Formula: see text], is the spectral fractional Laplacian operator, [Formula: see text], [Formula: see text], is a ...
Bisci, GM, Ortega, A, Vilasi, L
openaire   +6 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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